Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants in consumer goods, such as plastics, electronics, textiles, and construction material. PBDEs have been found in human milk, fat, and blood samples. Rodent studies indicate that PBDEs may be detrimental to neurodevelopment, possibly by lowering thyroid hormone concentrations in blood. In the present study, we determined c...

Thyrotropin-releasing hormone (TRH)-degrading activity was investigated in human cord, maternal, and euthyroid adult sera by measuring (a) the rate of disappearance of TRH and (b) the rate of formation of degradation products. The rate of TRH degradation in cord and maternal sera was 25-33% of that in euthyroid adult serum. Concomitantly, in cord and maternal sera, the rate of formation of prol...

background: acyclovir (acv), a synthetic purine nucleoside analogue, is known to be toxic to gonads. objective: the current study evaluated cytotoxicity of acv on histopathological changes in testis tissue and serum testosterone and lipid peroxidation concentrations of male rats. materials and methods: animals were divided into five groups. one group served as control and one group served as co...

objective: the present study was performed to compare the antioxidant effect of two different doses of zinc on lipid oxidation in type 2 diabetic patients. materials and methods: this double-blind, randomized controlled trial was conducted on 60 type 2 diabetic patients in yazd diabetes research center in 2008. the subjects were randomly allocated to receive zinc sulfate (iran, alhavi) either 2...

Objective: The effect of herbal medicine is more useful than synthetic medicines. The present research paper aims to show the effects of leaves extracts of Zizyphus Spina Christi (ZSC) on lipid profile, lipid peroxidation and activities of aminotransferase enzymes in streptozocin induced diabetic adult male rats. Materials and Methods: Fifty six male rats weighing 150-200 gm were included in t...

BACKGROUND Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in many products and have been detected in human samples worldwide. Limited data show that concentrations are elevated in young children. OBJECTIVES We investigated the association between PBDEs and age with an emphasis on young children from Australia in 2006-2007. METHODS We collected human blood serum samples ...

Brain-derived neurotrophic factor (BDNF) is a neurotrophin essential for neuronal survival and differentiation. We examined the concentration of BDNF in cord serum from newborns exposed to methylmercury (MeHg) and polychlorinated biphenyls (PCB) in utero by maternal consumption of whale meat. The cohort consisted of 395 singleton births (206 boys and 189 girls), gestational age ranging from 38 ...