The preparation of alkynes from carbonyl compounds via a one-carbon homologation has become a very useful pathway for the synthesis of acetylenic compounds, both internal and terminal. This tutorial review provides an overview of the different methods available for this transformation, including their scope and limitations, recent developments and applications in total syntheses.

BACKGROUND & OBJECTIVES A longitudinal study on social determinants of malaria has been undertaken in different villages of Ramgarh PHC of Jaisalmer district, Rajasthan. The study aims to determine social determinants of malaria as applicable to existing cast groups of desert part of Rajasthan. METHODS Out of 940 households in five villages, 150 households of Rajput community (forward communi...

Most studies on termite food selection have focused on a single nutrient per choice, however, termites, like all animals, must balance multiple nutrients in their diet. While most studies that use multi-nutrient approaches focus on macromolecules, the ability to balance the intake of inorganic nutrients is also vital to organisms. In this study, we used the geometric framework to test the effec...

Introduction Conclusions References

Implementation period CDRI was established in 1951 and has pursued various broad-based and long-term drug development projects over the ensuing five decades.This approach has led to the development of a pipeline of products from natural resources, including the commercialization of at least five lead compounds or products: gugulipid (hypolipidaemic), Bacopa monniera standardized fraction (memor...

Deformation microstructures are widely used for reconstructing tectono-metamorphic events recorded in rocks. In crustal settings deformation is often accompanied and/or succeeded by fluid infiltration and dissolution-precipitation reactions. However, the microstructural consequences of dissolution-precipitation in minerals have not been investigated experimentally. Here we conducted experiments...

Indol-2-ylmethyl carbanions stabilized by alkoxycarbonyl, cyano or benzenesulfonyl groups react with nitroarenes to form σH-adducts, which in the presence of base (triethylamine or DBU) and trimethylchlorosilane transform into indolo[3,2-b]quinoline derivatives in moderate to good yields.

We present the experimental and simulation results of two-dimensional optical coherent correlation spectroscopy signals along the phase-matching direction k(I) = -k(1) + k(2) + k(3) projected on the two-dimensional (2D) (Omega(3),Omega(2)) plane corresponding to the second and third delay periods. Overlapping Raman coherences in the conventional (Omega(3),Omega(1)) 2D projection may now be clea...

Migrating monarch butterflies (Danaus plexippus) use a time-compensated sun compass to navigate from eastern North America to their overwintering grounds in central Mexico. Here we describe the neuronal layout of those aspects of the butterfly's central complex likely to establish part of the internal sun compass and find them highly homologous to those of the desert locust. Intracellular recor...