In the title compound, [CuCl(C17H19Cl4N3)]ClO4, the Cu(II) ion adopts a distorted square-planar geometry defined by one chloride ligand and the three nitro-gen atoms from the bis-[(pyridin-2-yl)meth-yl](3,5,5,5-tetra-chloro-pent-yl)amine ligand. The perchlorate counter-ion is disordered over three sets of sites with refined occupancies 0.0634 (17), 0.221 (16) and 0.145 (7). In addition, the het...

Ammonia is quantitatively oxidized by hydrogen peroxide to form nitrite, 7.63 ± 0.14 nmoles μmole H2O2. The reaction is accomplished within a minute occurring both at 4 and 20 C (P>0.1, n = 5). The reaction is mediated by copper (II) as it fails to occur in absence of copper; and is quantitatively reduced in presence of copper sequestering agents. The reaction requires the presence of free ammo...

The tumor-inhibitory jxitency of combinations of the cupric chelate of kethoxal bis(thiosemicarbazone) [Cu(II)KTS] with several compounds that cause inhibition of the synthesis of DNA by different biochemical mechanisms was assessed in Sarcoma 180 ascites cells. Cu(II)KTS prolonged the survival time of tumor-bearing mice, whereas neither cupric chloride, copper stéarate,nor kethoxal bis(thiose...