Abstract Study question Is the cost per oocyte lower in antagonist ovarian stimulation protocol vs progestin primed donation program? Summary answer The is program What known already 1. use of progesterone during effective blocking LH surge, and it does not affect number oocytes collected or quality embryos obtained. Progestins can be used orally are less expensive than GnRH analogues. These ne...

BACKGROUND In view of the current debate concerning possible differences in efficacy between the two GnRH analogues used in IVF stimulated cycles, the current study aimed to explore whether progesterone control in the late follicular phase differs when GnRH antagonist is used as compared with GnRH agonist, and if so, to what extent the progesterone rise affects the probability of pregnancy. M...

GnRH antagonist negatively affects endometrial receptivity in in vitro fertilization (IVF) cycles, however, its underlying mechanism remains unclear. To explore its target molecules, we studied endometria in the window phase of fixed GnRH antagonist, low-dose flexible GnRH antagonist, GnRH agonist long protocol, and untreated control groups. There were 384 differentially expressed genes (DEGs) ...

BACKGROUND The selection of developmentally competent human gametes may increase the efficiency of assisted reproduction. Spermatozoa and oocytes are usually assessed according to morphological criteria. Oocyte morphology can be affected by the age, genetic characteristics, and factors related to controlled ovarian stimulation. However, there is a lack of evidence in the literature concerning t...

The recent introduction of GnRH antagonists in assisted reproductive technologies (ART) has simplified ovarian stimulation (1). This is mainly due to the immediate mode of antagonist action, which allows their administration during the follicular phase, when the inhibition of premature LH surge is required. In this way, the prolonged period of downregulation, necessary in the long agonist proto...

BACKGROUND Given the controversies regarding the effectiveness of gonadotropin-releasing hormone (GnRH) antagonists in prevention of ovarian hyper stimulation syndrome stimulation, this study was designed to compare GnRH agonist protocol with GnRH antagonist protocol in patients who were candidate for assisted reproductive techniques (ARTs). MATERIALS AND METHODS This investigation was perfor...

OBJECTIVE To report two cases with GnRH agonist triggering and a freeze-all approach in a GnRH antagonist protocol resulting in the development of severe ovarian hyperstimulation syndrome (OHSS), requiring hospitalization and peritoneal drainage. DESIGN Two case reports. SETTING A tertiary referral center and an obstetrics and gynecology department of a hospital. PATIENT(S) Case 1 and cas...

crestal bone loss is a biological complication in implant dentistry. the aim of this study was to compare the effect of progressive and conventional loading on crestal bone height and bone density around single osseointegrated implants in the posterior maxilla by a longitudinal radiographic assessment technique.twenty micro thread implants were placed in 10 patients (two implants per patient). ...

BACKGROUND Many factors from the oocyte/sperm or the process of fertilization may affect the zygote formation. The zygote score (Z-score) describes the quality of a human zygote based on its pronuclear morphology, nucleolar precursor bodies, and alignment of polar bodies, and it can be used in the selection process at the zygote stage for embryo transfer or cryopreservation. OBJECTIVE The aim...