نتایج جستجو برای: continuous infusion
تعداد نتایج: 310036 فیلتر نتایج به سال:
The delivery of drugs into systemic circulation via skin has generated much attention during the last decade. Transdermal therapeutic systems propound controlled release of active ingredients through the skin and into the systemic circulation in a predictive manner. Drugs administered through these systems escape first-pass metabolism and maintain a steady state scenario similar to a continuous...
conclusions the results of our study indicate that for patients who are scheduled for hip surgery, both continuous paravertebral and continuous epidural analgesia are effective in controlling postoperative pain but that the former has several crucial advantages. results mean arterial pressure was significantly lower in the epidural group compared with the paravertebral group from 2 hours after ...
The purpose of this study was to describe the nonlinear pharmacokinetics of piperacillin observed during intermittent infusion and continuous infusion by using a nonparametric population modeling approach. Data were 120 serum piperacillin concentration measurements from eight adult cystic fibrosis (CF) patients. Individual pharmacokinetic parameter estimates during intermittent infusion or cont...
Sexually dimorphic growth hormone (GH) secretory pattern is important in the determination of gender-specific patterns of growth and metabolism in rats. Whether GH secretion in humans is also sexually dimorphic and the neuroendocrine mechanisms governing this potential difference are not fully established. We have compared pulsatile GH secretion profiles in young men and women in the baseline s...
Emergency standard open tracheostomy is performed in impending or actual cardiac and respiratory-cardiac arrest. Indications are rare, but the procedure must be safe and rapidly effective. Neither facilitating (but risky) neck manipulations nor electrocautery are required nor, because of the urgency to obtain airway ingress, are bilateral traction stitches applied. No intravenous line should be...
Interferon has been shown to have an antiproliferative effect on leukaemic blast cells in vitro [ l , 3, 41. In short-term liquid culture, 50% inhibition of growth is achieved at IFN-a concentrations of 103 units/ml using myeloblasts derived from patients with acute myelogenous leukaemia (AML) [5]. Pharmacokinetic studies in patients receiving IFN-a by continuous intravenous infusion (i.v.i) ha...
5-Fluorouracil (5-FU) is a key anticancer drug that for its broad antitumor activity, as well as for its synergism with other anticancer drugs, has been used to treat various types of malignancies. In chemotherapeutic regimens, 5-FU has been combined with oxaliplatin, irinotecan and other drugs as a continuous intravenous infusion. Recent clinical chemotherapy studies have shown that several of...
BACKGROUND We retrospectively studied associations between bolus infusion of hydrocortisone and variability of the blood glucose level and changes in insulin rates in intensive care unit (ICU) patients. METHODS 'Glycemic variability' and 'insulin infusion rate variability' were calculated from and expressed as the standard deviation (SD) of all blood glucose levels and insulin infusion rates ...
We investigated the effect of beta-adrenergic stimulation on the heart rate and QT interval in syncope children with or without coexisting ventricular arrhythmias (VA). Of the 24 children who presented with syncope or presyncope and showed negative tilt test, 13 were classified into a group with VA and the remaining 11 without VA. The provocative test was performed in bolus infusion and continu...
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