Flavonoids are a diverse group of plant secondary metabolites, known to reduce inflammatory bowel disease symptoms. How they achieve this is largely unknown. Our study focuses on the gut epithelium as it receives high topological doses of dietary constituents, maintains gut homeostasis, and orchestrates gut immunity. Dysregulation leads to chronic gut inflammation, via dendritic cell (DC)-drive...

Background & Aim: Fabaceae plant family cow tail (Smirnovia iranica) is one of the valuable species of native shrubs and sand dunes in the central region of Iran which is consistent with the production of forage and soil conservation and creating a beautiful landscape; it has the active ingredients of medicinal values. The purpose of this study was to investigate the presence of some p...

By-products obtained from winemaking processes still contain large amounts of phenolic compounds, especially phenolic acids, flavanols, flavonols, stilbenes, and flavonoids. Enzymatic hydrolysis was used for determination and characterization of phenolic acids, flavanols, flavonols, and stilbenes. Characterization of the flavonoids was achieved using acid hydrolysis with 0.1% hydrochloric acid....

Anthocyanins belong to a class of flavonoids that exhibit important anti-oxidant and anti-inflammatory actions as well as chemotherapeutic effects. However, little is known concerning the molecular mechanisms by which these activities are exerted. In this study, we investigated the anthocyanins isolated from Vitis coignetiae Pulliat for their potential anti-proliferative and apoptotic effects o...

Background Flavonoids are well known for their vasodilatation activity. Their mechanism of action is still to be elucidated. Bilitranslocase is a bilirubin-specific membrane carrier that is also responsible for the ATP-independent transport of flavonoids across the cell membrane [1]. Recently, the expression of bilitranslocase in the endothelium has been characterized [2]. The aim of the study ...

ABSTRACT: In this study, response surface methodology was used to optimize ultrasound osmotic pretreatment with finished freeze drying of black cherries. Freeze drying is a separation process based on the  sublimation phenomenon. This process has the following advantages as compared to the conventional drying process, maintenance of the structure, moisture removal at low temperature (reduced tr...

Anthocyanins in the fruit of the Chinese bayberry (Myrica rubra Sieb. & Zucc.) are a major focus of research. In the current study, we investigated anthocyanin, total flavonoid, and phenolic acid profiles, as well as the expression of genes involved in anthocyanin biosynthesis, during fruit development in eight cultivars of Chinese bayberry. Total flavonoid and phenolic acid levels were relativ...

The objective of this study is to investigate the influence of cultivar and industrial processing on total polyphenols, anthocyanins, hydroxycinnamic acids and antioxidant activity in concentrated sour cherry (Prunus cerasus L., cvs. Marasca and Oblačinska) juices. Samples were collected during four processing steps: from fresh fruit prior to processing, then from pressed, filtered and concentr...

The flavonoids are aromatic secondary plant metabolites, which belong to the class of plant polyphenolics. Structurally they are heterocyclic π-electron systems built upon a C6H5(A)-C3-C6H5(B) flavone skeleton in which oxygen is the heteroatom. A group of flavonoids is differentiated in several classes according to the degrees of oxidation and unsaturation of the heterocyclic C ring. Because of...

Nowadays it is accepted that natural flavonoids present in fruits and plant-derived-foods are relevant, not only for technological reasons and organoleptic properties, but also because of their potential health-promoting effects, as suggested by the available experimental and epidemiological evidence. The beneficial biological effects of these food bioactives may be driven by two of their chara...