OBJECTIVE To evaluate the relative contribution of left ventricular (LV) geometric remodeling and of morphological and functional myocardial changes in rats with induced supravalvar aortic stenosis (SAS), in the transition from compensated hypertrophy to congestive heart failure (CHF). METHODS Twenty one weeks after induction of SAS, the rats were classified as controls (CG, n=13), without co...

Increasing attention is being focused on the role(s) that obesity may play in the development of cardiovascular disease, particularly congestive heart failure (CHF).1,2 Several indirect or associated effects are potential culprits. For example, obesity is strongly associated with many atherosclerotic risk factors, including arterial hypertension, insulin resistance, diabetes, and dyslipidemia.3...

BACKGROUND Sympathetic activation and respiratory abnormalities may each be implicated in the pathophysiology of congestive heart failure (CHF). Chemoreflexes are an important mechanism regulating both sympathetic drive and breathing. We therefore tested the hypothesis that chemoreflex function is altered in CHF. METHODS AND RESULTS We compared ventilatory, sympathetic, heart rate, and blood ...

OBJECTIVES The purpose of this study was to define the contribution of ischemic mitral regurgitation (IMR) to the occurrence of congestive heart failure (CHF) after myocardial infarction (MI). BACKGROUND After MI, CHF is a frequent and serious complication, but its determinants and, particularly, the role of IMR are poorly defined. METHODS We analyzed 173 asymptomatic patients with previous...

A non-invasive system to accurately and consistently monitor patients with congestive heart failure (CHF) has been designed, developed, and undergone preliminary testing. The system measures both bioimpedance and heart rate of a CHF patient after a hospital discharge. It consists of an electrodeembedded floor mat and a mountable visual display. The mat form factor is intended to integrate into ...

BACKGROUND Circulating CD34+ endothelial progenitor cells (EPCs) are capable of differentiating into mature endothelial cells to assist in angiogenesis and vasculogenesis. We sought to quantify the numbers of apoptotic progenitors in patients with congestive heart failure. METHODS AND RESULTS Peripheral blood mononuclear cells were isolated by Ficoll density-gradient from 58 patients with var...

OBJECTIVES To create a valid, sensitive, disease-specific health status measure for patients with congestive heart failure (CHF). BACKGROUND Quantifying health status is becoming increasingly important for CHF. The Kansas City Cardiomyopathy Questionnaire (KCCQ) is a new, self-administered, 23-item questionnaire that quantifies physical limitations, symptoms, self-efficacy, social interferenc...

OBJECTIVE We investigated participation levels and relationships among cognition, depression, and participation for people with severe congestive heart failure (CHF). METHOD People with severe CHF (New York Heart Association Class III or IV) awaiting heart transplantation (N = 27) completed standardized tests of cognition and self-report measures of executive dysfunction, depressive symptoms,...

INTRODUCTION: Thirst sensation in Congestive Heart Failure (CHF) patients is caused by diuretic administration and fluid consumption limitation. Unhandled thirst leads to a disobedient patient limitation that causes the condition worsen. This research aimed analyse frozen strawberries administration's effects on with CHF . MATERIAL AND METHOD: The method used was quasi-experiment pre-test post-...

PURPOSE OF REVIEW The present review will examine the prognostic importance of atrial fibrillation and heart failure, explore the different therapeutic options for treating atrial fibrillation and present the results of the Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial. RECENT FINDINGS The Atrial Fibrillation and Congestive Heart Failure trial was a randomized trial involvin...