Medical and surgical breakthroughs in the care of children born with heart defects have generated a growing population of adult survivors and spawned a new subspecialty of cardiology: adult congenital heart disease. The prevalence of adult congenital heart disease is escalating at a rampant rate, outpacing the relatively static prevalence of pediatric congenital heart disease, because adults no...

BACKGROUND Transforming growth factor-β receptor II (TGFBR2) is a key component of TGF-β signaling pathway. TGFBR2 can be detected in the generation of heart. The mouse embryos of TGFBR2 gene knockout exhibited congenital heart defects. METHODS We conducted a case-control study to investigate the association between TGFBR2 gene polymorphisms and congenital heart defects in Han Chinese populat...

Background—This study determines the prevalence of Congenital Heart Defects (CHD), diagnosed prenatally or in infancy, and fetal and perinatal mortality associated with CHD in Europe. Methods and Results—Data were extracted from the European Surveillance of Congenital Anomalies central database for 29 population-based congenital anomaly registries in 16 European countries covering 3.3 million b...

In recent years, advances in transcatheter percutaneous closures for adults with congenital heart defects have paralleled technological improvements, including imaging, arrhythmia management, and percutaneous interventions. Indications for percutaneous closure of congenital heart defects have expanded with the widening range of device shapes and sizes. This review gives a brief outline of accom...

cor triatriatum   sinistrum is a rare congenital cardiac malformation, accounting for about 0.1-0.4% of all congenital heart diseases and characterized by the presence of a fibromuscular membrane that subdivides the left atrium into two chambers in the classical form. while classic cor triatriatum in most patients can be observed during the neonatal period or early infancy, it is very rare in a...

a 29-year-old woman was referred to our hospital due to exacerbation in dyspnea on exertion and easy fatigability. a known case of congenitally corrected transposition of the great vessels and congenital complete heart block, she had already received a permanent single-chamber pacemaker. decision was made to implant a biventricular pacemaker for the treatment of the failing heart. excellent cor...

background: neonatal lupus erythematosus is an uncommon disease. congenital complete heart block (cchb) usually happens in neonates with maternal systemic lupus erythematosus. the most prevalent presentation of cchbis bradycardiathatcanbediagnosed through an electrocardiogram. case report: here in, we present the case of a full-term male neonate with gestational age of 37 weeks and birth weight...