BACKGROUND Paternal occupational exposures to potential health hazards are likely to affect congenital malformations through the spermatogenesis cycle. PURPOSE The aim of this case-control study was to assess the relationship between the risk of musculoskeletal congenital malformations in offspring and paternal workplace exposure to potential health hazards during the preconception period. ...

CCAM is a rare conolition in the neonatal Period. Two babies were admitted to Mofid hospital with cyanosis and respiratory distress. Pneumectomy was done for both of them for space occupaying lesion. Pathology examination of first case showed area of cuboidal epithelium lined tubes and spaces resembling fetal bronchioles, which are torn in folds. In second case, pathologic examination revealed...

Anorectal Malformations are known to be associated with various other congenital anomalies including duodenal atresia. An association of congenital intrinsic duodenal obstruction causing partial duodenal obstruction in a patient with anorectal malformation is not described in literature. We describe a case of delayed presentation of congenital intrinsic duodenal obstruction in a child with high...

BACKGROUND It has been hypothesised that cerebral palsy (CP) and other congenital anomalies are attributable to feto-fetal transfusion problems in a monochorionic multiple gestation. Thus more than one organ could be compromised leading to the coexistence of two or more anomalies in a fetus. Such anomalies in a singleton birth may be attributable to early demise of the co-conceptus as a vanishi...

Pediatric respiratory disease related to congenital and genetic etiologies are important topics found on the USMLE. Congenital disease to be aware of include Diaphragmatic hernias, congenital cystic adenomatoid malformation, surfactant deficiency, pediatric pulmonary hypoplasia, and bronchopulmonary dysplasia. Genetic disease to be aware of include cystic fibrosis, alpha 1 antitrypsin, and prim...

We evaluated the incidence of congenital malformations in 566 children (median age: 8, M:F 1.3) with lymphomas and solid tumors using patient records. In this study, 12.7% of children either had a congenital malformation (7.8%) or a birthmark (4.9%). The incidence of patients with a childhood cancer syndrome was 3% and these cases developed typical tumors. The rate of consanguineous marriages w...

BACKGROUND Isolated congenital asplenia is a poorly understood and rare form of primary immunodeficiency, often associated with life-threatening infections. CASE REPORT We encountered a unique case of a 22-year-old asplenic male who presented with severe iron-deficiency anemia secondary to occult gastrointestinal bleeding since age 15. Our extensive work-up confirmed jejunal arteriovenous malfo...

A Univentricular Heart (UVH) is a rare congenital heart malformation. Prognosis without surgical intervention is considered to be poor and survival into the adulthood is unusual (1, 2). Its incidence being 1% to 4.3% of all congenital heart defects. Here we reported this rare congenital heart defect; hence it was worth reporting this interesting case.

the village of Connihatty, Zillah Kajshahye, and presents the following peculiar malforraities:? (a.) Spine.?An angulo-lateral curvature is seen occupying the whole of the dorsal region; the lateral deflexion is towards the right; all the ribs from the 3rd downwards participate in the curve, and are greatly bent at their angles. (b.) Hands (1) Right.?Fingers normal, but the metacarpal bone of t...