BACKGROUND Non-concordance with medication remains a major public health problem that imposes a considerable financial burden on the health care system, and there is still a need for studies on correlates of non-concordance. Our first aim is to analyse whether any of the individual characteristics age, educational level, financial strain, self-rated health, social participation, and trust in th...

OBJECTIVE The aim of this study was to determine the intra and interobserver concordance rates of the Waldenström, Catterall and Herring classifications for Legg-Calvé-Perthes disease. METHODS One hundred radiographs of the pelvis in anteroposterior and Lauenstein views, from patients with this disease, were selected. The radiographs were classified by four physicians with different levels of...

conclusions although the presence of pni in prostate biopsy is accompanied by higher surgical stages, pni is not an appropriate independent factor in risk stratification. patients and methods this cross-sectional study was conducted using a sample of 109 patients who attended a tertiary health care center from 2008 to 2013. the selection criteria were pni in prostate biopsy with gleason scores ...

The question about the definition of concordance between random vectors is an open problem because there is not an unanimous opinion about its meaning and its appropriate definition. Also the definition of multivariate risk measures encounters many difficulties. In this paper we want to investigate the relationship between these multivariate measures, essentially based on the relation between r...

We define the concordance crosscap number of a knot as the minimum crosscap number among all the knots concordant to the knot. The four-dimensional crosscap number is the minimum first Betti number of non-orientable surfaces smoothly embedded in 4-dimensional ball, bounding the knot. Clearly the 4-dimensional crosscap number is smaller than or equal to the concordance crosscap number. We constr...

Clinical expertise derived from experience forms the foundation of personal knowledge and skills which is a comprehensive part of healthcare professional’s clinical decision making in practice. 1 Physical therapy (PT) had evolved through an ongoing paradigm shift towards evidence-informed practice (EIP) in all aspects of clinical practice, academic education, scientific research and professiona...

Main decision-making problems can be described into choice, ranking or sorting of a set of alternatives or solutions. The principle of Electre TRI (ET) method is to sort alternatives ai according to criteria g j into categories Ch whose lower and upper limits are respectively bh and bh+1. The sorting procedure is based on the evaluations of outranking relations based firstly on calculation of p...

Nuclear matrix proteins (NMPs) show promise as informative biomarkers in following the pathogenesis of breast cancer. The nuclear matrix is a dynamic RNA-protein network involved in the organization and expression of chromatin. Cisplatin, which preferentially cross-links nuclear matrix proteins to DNA in situ, may be used to identify NMPs that organize and/or regulate the processing of DNA. In ...

According to current policy, chemicals are evaluated for possible cancer risk to humans at low dose by testing in bioassays in which high doses of the chemical are given to rodents. Thus, risk is extrapolated from high dose in rodents to low dose in humans. The accuracy of these extrapolations is generally unverifiable because data on humans are limited. However, it is feasible to examine the a...