We found that development of obesity was coupled with emergence of a progressively worsening deficit in neural reward responses. Similar changes in reward homeostasis induced by cocaine or heroin are considered to be crucial in triggering the transition from casual to compulsive drug-taking. Accordingly, we detected compulsive-like feeding behavior in obese but not lean rats, measured as palata...

This study aims to investigate the factors contributing online impulsive and compulsive buying behaviours among Vietnamese consumers, given increasing prevalence of shopping. A survey 562 participants (104 offline 548 online) Partial least squares structural equation model (PLS-SEM) were recruited empirically examine proposed research model. We found that (1) Performance Expectancy, Facilitatin...

Objective: This study was designed to examine the effect of environmental enrichment during methamphetamine (METH) dependency and withdrawal on methamphetamine-induced spatial learning and memory deficits and obsessive-compulsive behavior. Method: Adult male Wistar rats (200 ± 10 g) chronically received bi-daily doses of METH (2 mg/kg, sc, with 12 hours intervals) for 14 days. Rats reared in st...

Parents of autistic probands with high and low rates of repetitive behaviors were compared for rates of obsessive-compulsive traits and disorder. The rate of repetitive behaviors was assessed using the Autism Diagnostic Interview-Revised (ADI-R) in 176 autistic probands from 57 multiplex families. Obsessive-compulsive disorder (OCD) in parents was determined by direct interview using a parental...

In our recently published article, we investigated the behavioral addiction model of obsessive-compulsive disorder (OCD), by assessing three core dimensions of addiction in patients with OCD healthy participants. Similar to the common findings in addiction, OCD patients demonstrated increased impulsivity, risky decision-making, and biased probabilistic reasoning compared to healthy controls. Th...

We report here, a young male patients referred with “Obsessive Compulsive Disorder” symptoms which emerged after the successful treatment of pineal germinoma. OCD (obsessive-compulsive disorder) is a frequent, chronic, and clinically disorder which may presents in several neurologic disorders, especially occurs, in early adult life. Essential features of OCD are obsessional thoughts, compulsive...

OBJECTIVE Tabernaemontana divaricata (TD) from Apocynaceae family offers the traditional folklore medicinal benefits such as an anti-epileptic, anti-mania, brain tonic, and anti-oxidant. The aim of the present study was to evaluate the effect of ethanolic extract of TD leaves on burying behavior in mice. MATERIALS AND METHODS Mice were treated with oral administration (p.o.) of ethanolic extr...