The impact damage response of balsa core sandwich composite plates with S2-glass/ epoxy reinforced facesheets is evaluated by impacting them with a spherical steel projectile at single impact locations. The impact damage can significantly reduce the structural integrity and load bearing capacity of a composite structure. Under high velocity impact loading, laminated composites experience signif...

Novel submicron core-shell-structured chitosan-based composite particles encapsulated with enhanced green fluorescent protein plasmids (pEGFP) were prepared by complex coacervation method. The core was pEGFP-loaded thiolated N-alkylated chitosan (TACS) and the shell was pH- and temperature-responsive hydroxybutyl chitosan (HBC). pEGFP-loaded TACS-HBC composite particles were spherical, and had ...

Novel bioresorbable core/shell composite fiber structures loaded with proteins were developed and studied. These unique polymeric structures are designed to combine good mechanical properties with a desired controlled protein-release profile, to serve as scaffolds for tissue regeneration applications. Core/shell fiber structures were formed by "coating" poly(L-lactic acid) fibers with protein-c...

This paper reports the measurement and modelling of magnetic properties of SOMALOY 500, a soft magnetic composite (SMC) material, under different 2D vector magnetisations, such as alternating along one direction, circularly and elliptically rotating in a 2D plane. By using a 2D magnetic property tester, the B-H curves and core losses of the SMC material have been measured with different flux de...

Background. Understanding how disease-assessment indices perform in rheumatoid arthritis (RA) clinical trials can inform their use in routine practice. The study objective was to assess the capacity of combinations of RA Core Data Set measures to distinguish rituximab from control treatment. Methods. Post hoc analysis of two randomised clinical trials was used. Composite Efficacy Indices were d...

Over the last decade, magnetic iron oxide nanoparticles (IONPs) have drawn much attention for their potential biomedical applications. However, serious in vitro and in vivo safety concerns continue to exist. In this study, the effects of uncoated, FemOn-SiO2 composite flake-like, and SiO2-FemOn core-shell IONPs on cell viability, function, and morphology were tested 48 h postincubation in human...

This work presents a new method to prepare poly(sodium acrylate) magnetite composite nanoparticles. Core/shell type magnetite nanocomposites were synthesized using sodium acrylate as monomer and N,N-methylenebisacrylamide (MBA) as crosslinker. Microemulsion polymerization was used for constructing core/shell structures with magnetite nanoparticles as core and poly(sodium acrylate) as shell. Fou...

Although roughly 40% of pharmaceuticals being developed are poorly water soluble, this class of drugs lacks a formulation strategy capable of producing high loads, fast dissolution kinetics, and low energy input. In this work, a novel bottom-up approach is developed for producing and formulating nanocrystals of poorly water-soluble active pharmaceutical ingredients (APIs) using core-shell compo...

A piezoelectric composite containing the ferroelectric polar (Bi(Na0.8K0.2)0.5TiO3: f-BNKT) and the non-polar (0.94Bi(Na0.75K0.25)0.5TiO3-0.06BiAlO3: BNKT-BA) phases exhibits synergetic properties which combine the beneficial aspects of each phase, i.e., the high saturated polarization (Ps) of the polar phase and the low coercive field (Ec) of the non-polar phase. To understand the origin of su...