The pharmacological activity of herbal medicine is an overall action of each component in accordance with their original proportion. An efficient, sustained, and controlled-release drug delivery system of herbal medicine should ensure the synchronized drug release of each active component during the entire release procedure. In this study, silymarin (SM), a poorly soluble herbal medicine, was s...

Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, and Fructus Gardeniae are often used alongside with clozapine (CLZ) for schizophrenia patients in order to reduce side effects and enhance therapeutic efficacy. However, worse outcomes were observed raising concern about a critical issue, herb-drug interactions, which were rarely reported when antipsychotics were included. This study aims t...

Tuberculosis was declared as a global pandemic and panic because the causative Mycobacterium tuberculosis can kill an incredible number of individuals which formulate a major obstacle to social and economic development of the country. Most of the developing countries are affected by tuberculosis. Antitubercular therapy involves the use of Directly Observed Therapy Short (DOTS) course for 6-9 mo...

Herbal medicines are now in great demand in the developing world for primary health care not because they are inexpensive but also for better cultural acceptability, better compatibility with the human body and minimal side effects. However, recent findings indicate that all herbal medicines may not be safe as severe consequences are reported for some herbal drugs. Most herbal products on the m...

WHO has been publishing guidelines for assessment of quality of herbal raw material from time to time, however now it is emphasizing on standardization of herbal preparations. As there are different kinds of preparations available in the traditional systems, a common technique of standardization is not available. This article reviews the recent techniques that are used in herbal drug standardiz...

BACKGROUND: There is a global as well national resurgence and revival of faith in drugs of plant origins. WHO has played a significant role in recognizing the relevance of these in today’s world. Herbal formulations and traditional medicines are generally polyherbal consisting of numerous bio-molecules because of which their identification and characterization is difficult. Also there are simil...

BACKGROUND The increasing use of herbal drugs and their easy availability have necessitated the use of mutagenicity tests to analyze their toxicity and safety. OBJECTIVES The aim of this study was to determine the in vitro mutagenicity of Artemisia draconculus L., a herbal drug, by performing single cell gel electrophoresis (SCGE). MATERIALS AND METHODS In this study, we obtained a herbal d...

Herbal combination preparations are widely used in traditional herbal medicine and are even established as modern evidence-based herbal medicinal products. The rationale behind such combinations is often questioned and assessing the contribution of each of the combination partners to overall activity is challenging. STW 5 (Iberogast) is such a combination with confirmed clinical efficacy in fun...

Use of herbal medicines dates back long history. These days the use of herbal medicines has increased because of their ability to treat different diseases with fewer side effects. However, the effective drug delivery of herbal medicines has not still been achieved. Different scientific approaches are being developed these days to deliver herbal medicines. Novel formulations including nanopartic...

Introduction The continued use of herbal medicine in the United States and among members of Kaiser Permanente (KP) makes an updated review of this topic timely and important. Many pharmacies at KP facilities in Southern California now carry traditional herbal preparations. These “dietary supplements” are over-the-counter therapy that is not routinely screened for drug interaction by the pharmac...