نتایج جستجو برای: colorectal cancer
تعداد نتایج: 925796 فیلتر نتایج به سال:
Introduction: Colorectal cancer is the most common cancer of the alimentary system. In women, it is the second leading cause of mortality after breast cancer while in men, it is the third leading cause of death after lung and prostate carcinoma. Prevalence is more in population older than 50 years and increases in older people. Therefore, best treatment and prognosis is early diagnosis of disea...
Background and Objective: Mesenchymal stem cells (MSCs) promote metastasis in colorectal cancer; however, the mechanism underlying this process is not fully understood. Epithelial to mesenchymal transition (EMT) is a key step in tumor acquisition of metastatic phenotype. We aimed to investigate the effect of MSCs on the expression of EMT markers, as well as cancer stem cell markers in HT-29 col...
Introduction: In recent studies, methylation of FOXE1 in colorectal cancer has been reported as a diagnostic biomarker. In this study for the first time, the expression of FOXE1 and PTCSC2 in colorectal cancer was investigated and their expression patterns in two healthy and tumor tissues of patients were compared. Methods: In this study, 40 tumor tissues with colorectal cancer and 40 adjacent...
Background: Human colorectal cancer cells overexpress carcinoembryonic antigen (CEA). CEA is a glycoprotein which has shown to be a promising vaccine target for immunotherapy against colorectal cancer. Objective: To design a DNA vaccine harboring CEA antigen and evaluate its effect on inducing immunity against colorectal cancer cells in tumor bearing mice. <str...
Using standardized forms for prescription and administration of medications is one of the main solutions for reducing medication errors in the chemotherapy process. Considering the high prevalence and mortality rate of colorectal cancer, in this study we tried to design and validate a standard printed form and evaluate oncologists’ and nurses’ adherence to this form. This cross-sectional study ...
Introduction: Detection of malignant cells in the peritoneal cavity indicates the extension of cancer cells. The aim of this study is to evaluate the incidence rate of positive cytology in colorectal cancer and its relationship with the local progress of the tumor. Methods: In a 2-year prospective study in Mashhad and Iran Universities of Medical Sciences, peritoneal lavage was performed on...
Background: Colorectal cancer is a common cancer and has a high rate of mortality and morbidity. This can be reduced by screening tests. Some of the studies have recently referred to Red Cell Distribution Width (RDW) as a marker for early detection of various cancers. The aim of this study was to investigate the RDW and early detection of colorectal cancer and polyp. M...
Background: Colorectal cancer is a major cause of morbidity and mortality throughout the world, and its treatments include surgery, chemo-radiotherapy. Despite improvements in clinical outcomes of patients with this tumor over the past decades, prognosis remains poor with a 5-year survival rate of <10%. Angiogenesis inhibitor agents have been recently added to the treatment regimen of this dise...
سرطان کولون و رکتوم یکی از انواع شایع - سابقه ابتلا به سرطان کولورکتال یا پولیپ های سرطانهاست که با وجود ایجاد مشکلات و عوارض متعدد در سلامتی انسانها، هنوز به طور جدی و کافی مورد توجه قرار نگرفته است. به طوریکه در سال ۲۰۰۴ بیش از ۱۳۰ هزار مورد جدید ابتلا به این بیماری در امریکا گزارش شده است. و طبق آمارهای انجمن سرطان آمریکا در سال ۲۰۰۲، از ۱۸۳۳۰۰ مورد ابتلا به سرطان کولورکتال۵۶ هزار مورد ب...
aim : this study aims to investigate some clinical and pathologic factors associated with the prognosis of patients with colon and rectum cancers separately. background : colorectal cancer is the most common cancer of the digestive system and also the fourth cause of cancer-related deaths around the world. different studies indicate that survival of patients with colorectal cancer has improved ...
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