cold agglutinins are of unique relevance in cardiac surgerybecause of the use of hypothermic cardiopulmonary bypass (cpb). cold autoimmune diseases are defined by the presence of abnormal circulating proteins (usually igm or iga antibodies) that agglutinate in response to a decrease in body temperature. these disorders include cryoglobulinemia and cold hemagglutinin disease.immunoglobulin m aut...

arterial sclerosis has been extensively described but reports on venous sclerosis are very sparse. phlebosclerosis refers to the thickening and hardening of the venous wall. despite its morphological similarities with arteriosclerosis and potential morbid consequences, phlebosclerosis has gained only little attention. we report a 72 year old male with paralysis and atrophy of the right leg due ...

background: the incidence of colorectal cancer is rising in several developing countries. in the absence of integrated endoscopy and pathology databases, adenoma detection rate (adr), as a validated quality indicator of screening colonoscopy, is generally difficult to obtain in practice. we aimed to measure the correlation of polyp-related indicators with adr in order to identify the most accur...

introduction eating disorders and morbid obesity have become common over the recent years. laparoscopic gastric bypass surgery is known as one of the most effective methods for weight loss. due to the rarity of studies regarding the association of depression and surgery, we aimed to compare the levels of depression in patients with excessive obesity before and after gastric bypass surgery. conc...

Background and objective: Helicobacter pylori infection is one of the most common chronic bacterial infections in the world, especially in the developing countries. This bacterium is the cause of many diseases such as lymphoma, gastritis, peptic ulcers, and stomach cancer. According to recent reports, H. pylori infection can potentially increase the risk of colon cancer. The cu...

background the sitting position, rather than squatting, during defecation has been hypothesized to be a risk factor for colorectal cancer (crc). methods we conducted a case-control study to test this hypothesis. a total of 100 crc cases from two hospitals in iran and 100 control subjects, selected from the coronary care unit (ccu) of those same hospitals were selected for this study. we adminis...

curcumin exhibits both cancer- preventive activity and growth inhibitory effects on several neoplastic cells including human colon cancer. serotonin and its receptors have also been implicated in tumor development. this study investigated the effect of ritanserin, a selective serotonin 5ht2a receptor antagonist, alone and in combination with curcumin on colorectal cancer cell lines. results sho...

background: colon cancer is the third cause of cancer deaths. although colon cancer survival time has increased in recent years, the mortality rate is still high. the cox model is the most common regression model often used in medical research in survival analysis, but most of the time the effect of at least one of the independent factors changes over time, so the model cannot be used. in the c...