In order to survive and function properly, mammalian cells send and receive a vast number of signals that are used to adjust their behavior in response to changes in the environment. Among the multiple receptor systems that cells utilize for this purpose, the most prominent role is undoubtedly played by G protein-coupled receptors (GPCRs). These cell surface receptors respond to an incredibly w...

conclusions adherence to the meddiet, according to mds and sofi-mds, may not predict mets components and mets incidence after 3 years of follow-up in iranian adult populations. results after adjusting for potential confounders, neither higher mds nor higher sofi-mds were significantly associated with the mean values of mets components and the risk of metabolic abnormalities incidence after 3 ye...

Thromb Haemost 2005;3:1432-6. 4. Dashe JS, Ramin SM, Cunningham FG. The long-term consequences of thrombotic microangiopathy (thrombotic thrombocytopenic purpura and hemolytic uremic syndrome) in pregnancy. Obstet Gynecol 1998;91:662-8. 5. Miner PE, Nutt RL, Thomas ME. Thrombotic thrombocytopenic purpura occurring in pregnancy. Am J Obstet Gynecol 1955;70:611-7. 6. Weiner CP. Thrombotic microan...

introduction: cervical rib is relatively uncommon congenital abnormality that originates from the seventh cervical vertebrae and rarely from the sixth vertebrae. the purpose of this paper is to consider that this abnormal condition is an important cause of neurovascular compression at the thoracic outlet. methods: in this study all patients who were referred to radiology department of isfahan h...

introduction women with mosaic turner syndrome (ts) bearing the presence of y chromosome material or with complete androgen insensitivity syndrome (cais) is at risk of gonadal malignancy. two patients with characteristic features of these uncommon disorders are reported, and the surgical techniques of laparoscopic gonadectomy are reviewed and discussed. the aim of the present study is to report...

J oubert syndrome (JS) is an autosomal recessive disorder presenting with congenital hypotonia evolving into ataxia, developmental delay, and either oculomotor apraxia or abnormalities of respiratory pattern or both. JS is characterised, using magnetic resonance imaging (MRI), by cerebellar vermian hypoplasia and a complex brain stem malformation called the ‘‘molar tooth sign’’ (MTS), consistin...

an investigation was carried out on a young unrelated couple, both 29 years old, with two boys and three girls, 3 months to 8 years old. one boy and the mother were healthy, the other four children and the father were affected. the family, originally from the district of nour, in northern iran, near the caspian sea, was first counseled at the genetic clinic in tehran in 1984. several trips were...

thymoma is the most common neoplasm of anterior mediastinum with incidence peaks during the fourth, fifth and sixth decades of life. two-thirds of patients are asymptomatic and identified accidentally by chest x-rays . of the total, 40-70 % of patients have one or more parathymic syndromes of which myasthenia gravis (mg) is the most common and reported in 10-50% . gullain-barre syndrome (gbs) h...

conclusions there was a significant association between pms scores and the prevalence of metabolic syndrome. further studies are needed to confirm and validate the relationships between lipid profile abnormalities and metabolic disorders with pms. objectives this study was designed to investigate the association of hormonal and metabolic factors with pms among iranian women of reproductive age....