Changes in the coat cover are important for mammalian thermoregulation. This is especially true where variable environmental conditions exist throughout the seasons. Coat cover shedding is the replacement of old coat hair with new hair. The process differs in various equids. The aim of the study was to examine the changes in the coat of primitive Polish Konik horses living on a reserve in south...

UNLABELLED Icosahedral virus assembly requires a series of concerted and highly specific protein-protein interactions to produce a proper capsid. In bacteriophage P22, only coat protein (gp5) and scaffolding protein (gp8) are needed to assemble a procapsid-like particle, both in vivo and in vitro. In scaffolding protein's coat binding domain, residue R293 is required for procapsid assembly, whi...

BACKGROUND Between 20% and 30% of patients with clinically diagnosed hypertension have normal blood pressure (BP) values during automated ambulatory 24-hour BP monitoring. It has not been clear, however, whether these patients can be regarded as normotensive or whether they should be treated in the same way as confirmed hypertensive patients. METHODS AND RESULTS Ambulatory BP monitoring was p...

a research study was carried out on the indirect selection efforts amongst small scale holders of west african dwarf (wad) goats based on coat pigmentation and wattle types in ogbomoso, nigeria using personal interviews and structured questionnaires given using simple random on-farm techniques. the questionnaires were focused on the ownership distribution, preferred pigmentation and wattle type...

The aim of this study was to evaluate whether sustained hypertensives with high clinic blood pressure, despite multiple drug treatment, show a true resistant hypertension or a ‘‘white-coat effect,’’ and whether the pretreatment white-coat effect is maintained despite pharmacological therapy. The occurrence of resistant hypertension was determined in 250 consecutive essential hypertensives who h...

OBJECTIVES To determine the frequency of White Coat Hypertension in patients undergoing ambulatory blood pressure monitoring at a tertiary care center and to compare ambulatory blood pressure profiles of normotensives, white coat hypertensives and hypertensives. METHODS A descriptive cross-sectional study was conducted which included all adult patients undergoing ambulatory blood pressure mon...

The conserved coat protein complex II (COPII) mediates the initial steps of secretory protein trafficking by assembling onto subdomains of the endoplasmic reticulum (ER) in two layers to generate cargo-laden transport carriers that ultimately fuse with an adjacent ER-Golgi intermediate compartment (ERGIC). Here, we demonstrate that Trk-fused gene (TFG) binds directly to the inner layer of the C...

More than a decade of observations of dairy operations in Hawai‘i suggested that there were more black cows in the local dairy herds than white cows. Hence, the objective of the study was to investigate if hair coat color affected productive life of Holstein cows in the sub-tropics. Two large herds within 2,000 meters of each other in the Waianae Coast district were used. Lactating cows were cl...

We have reported variants of the M13 bacteriophage major coat protein (P8) that enable high copy display of monomeric and oligomeric proteins, such as human growth hormone and steptavidin, on the surface of phage particles (Sidhu SS, Weiss GA, Wells JA. 2000. High copy display of large proteins on phage for functional selections. J Mol Biol 296:487-495). Here, we explore how an optimized P8 var...

Long RNAs often exist as multiple conformers in equilibrium. For the genomes of single-stranded RNA viruses, one of these conformers must include a compacted state allowing the RNA to be confined within the virion. We have used single molecule fluorescence correlation spectroscopy to monitor the conformations of viral genomes and sub-fragments in the absence and presence of coat proteins. Cogna...