OBJECTIVES To study the effect of escitalopram and fluoxetine on coagulation profile in patients with major depression. METHOD This was a prospective, open-label, single-centre study in 40 patients diagnosed with major depressive disorder. The patients were diagnosed using Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. Twenty patients receiving escitalopram 10...

The blood is a very complex organ in our body and coagulation, in particular, is coordinated by various mechanisms. It is known from experience that in order to truly learn and comprehend the different coagulation processes and disorders, most medical students take much time and great pains. The topic is often regarded as not comprehensible and very abstract. This article is supposed to provide...

Evidence for the involvement of the sixth component of complement (C6) in normal blood coagulation is provided by the description of a coagulation abnormality in rabbits with a genetic C6 deficiency and by its correction with highly purified preparations of C6. Whole blood clotting time in glass or plastic was prolonged and prothrombin consumption was decreased in blood from the deficient anima...

introduction: the administration of crystalloid fluids is considered as the first line treatment in management of trauma patients. infusion of intravenous fluids leads to various changes in hemodynamic, metabolic and coagulation profiles of these patients. the present study attempted to survey some of these changes in patients with mild severity trauma following normal saline infusion. methods:...

 It has been recognized that patients with Cyanotic Congenital Heart Disease (CCHD) show significant bleeding tendency which can be secondary to coagulopathies in these patients. Some coagulation abnormalities are thrombocytopenia, factor deficiencies, fibrinolysis and Disseminated Intravascular Coagulation  (DIC). According to high prevalence of CCHD and major operations in theses patients, th...

MATERIAL/METHODS The animal experiments of coagulation therapy on the wound tissue bed during partial nephrectomy with an argon beam coagulator were performed on 16 rabbits, which were randomly divided into 4 groups. Groups A and B had renal artery occlusion; the treatment time of coagulation was 4 seconds and 6 seconds, respectively. Groups C and D did not have renal artery occlusion; the trea...

Birth asphyxia may predispose to haemostatic failure.The objective of this study was to evaluate coagulation profile of babies with birth asphyxia and correlate these values with their clinical characteristics. Clinico-laboratory characteristics and coagulation profiles of 41 consecutive full term babies who had birth asphyxia were evaluated. Their coagulation profiles were compared to another ...

BACKGROUND A bleeding diathesis is a common feature of Noonan syndrome, and various coagulation abnormalities have been reported. Platelet function has never been carefully investigated. METHODS The degree of bleeding diathesis in a cohort of patients with Noonan syndrome was evaluated by a validated bleeding score and investigated with coagulation and platelet function tests. If ratios of pr...

THE effect of alimentary lipemia on coagulation has been a matter of controversy for most of the past decade. Reports have confirmed and denied an acceleration of whole blood coagulation.'-'0 A considerable amount of evidence is growing that purports to show lipemia as a factor in the pathogenesis of thrombotic disease, and perhaps even a factor in the genesis of atheroselerosis.1' These specul...

it has been recognized that patients with cyanotic congenital heart disease (cchd) show significant bleeding tendency which can be secondary to coagulopathies in these patients. some coagulation abnormalities are thrombocytopenia, factor deficiencies, fibrinolysis and disseminated intravascular coagulation  (dic). according to high prevalence of cchd and major operations in theses patients, the...