Our objective was to investigate the efficacy and safety of capecitabine maintenance therapy (CMT) after capecitabine-based combination chemotherapy in patients with metastatic breast cancer. The clinical data of 139 metastatic breast cancer patients treated from March 2008 to May 2012 with capecitabine-based combination chemotherapy were retrospectively analyzed. When initial disease control w...

Contrary to a datacommunications network, a telecommunications network logically comprises two networks: a transport and a signaling network. The transport network carries voice traffic, while the signaling network carries the control information that is needed for the administration and supervision of calls, and the administration of the telecommunications network itself. Traditionally, signal...

Inherited neuropathies, collectively known as Charcot-Marie-Tooth disease (CMT), are a group of genetically and phenotypically heterogeneous peripheral neuropathies associated with mutations or copy number variations in over 80 distinct genes. 1 Named after the three neurologists who first described the condition in 1886, CMT is the most common inherited neuromuscular disease. 2 CMT is a motor ...

Tetracyclines (doxycycline and minocycline) inhibit inducible NO synthase expression and augment cyclooxygenase (COX)-2 expression and PGE2 production. In contrast, chemically modified tetracyclines (CMTs), such as CMT-3 and -8 (but not CMT-1, -2, and -5), that lack antimicrobial activity, inhibit both NO and PGE2 production in LPS-stimulated murine macrophages, bovine chondrocytes, and human o...

We investigate if concentrative meditation training (CMT) offered during adolescent development benefits subsystems of attention using a quasi-experimental design. Attentional alerting, orienting, and conflict monitoring were examined using the Attention Network Test (ANT) in 13-15 year old children who received CMT as part of their school curriculum (CMT group: N = 79) vs. those who received n...

Multi-homing at the transport layer is a mechanism that ties one transport layer association to several network interfaces at each communication host, which enabling the two end-nodes to exchange data over several network paths. Stream control transmission protocol (SCTP) supports multi-homing feature. We suggest Concurrent Multipath CommunicationSCTP (CMC-SCTP) which uses multi-homing as a bas...

With the advances of wireless communication technologies, wireless networks gradually become themost adopted communication networks in the new generation Internet. Computing devices and mobile devices may be equipped with multiple wired and/or wireless network interfaces. Stream Control Transmission Protocol (SCTP) has been proposed for reliable data transport and its multihoming feature makes ...

In recent years the number and diversity of networks available to mobile computing devices has increased dramatically. It is now feasible for a device to support multiple networks such as 3G, 802.3, 802.11 and even 802.16. Given the diversity of these networks in terms of range and bandwidth, there is a need to define a seamless approach to network handover. While current 802 standards provide ...

Studies of heterothallic and homothallic strains of Saccharomyces cerevisiae have led to the suggestion that mating-type information is located at three distinct sites on chromosome 3, although only information at the mating-type (MAT) locus is expressed (Hicks, Strathern and Herskowitz, 1977). We have found that the recessive mutation cmt permits expression of the normally silent copies of mat...