OBJECTIVE To study the association between analfissures and cow's milk allergy (CMA) in infants. METHODS AND METHOD: In a prospective study, 72 confirmed cases of CMA in infants were examined for anal fissure by pediatricians with five years' experience. A positive finding was defined as when an anal fissure was detected by at least two out of three examiners. RESULTS Of infants with CMA with...

The nature and evolutionary state of the diverse objects displaying the B[e] phenomenon are reasonably known, except for a rare subtype named FS CMa stars. These are surrounded by compact disks of warm dust whose origin is unclear. Although the luminosity of these objects corresponds to main-sequence stars, mass loss rates derived from emission lines are 2 orders of magnitude larger than predic...

Taking inspiration from approximate ranking, this paper investigates the use of rank-based Support Vector Machine as surrogate model within CMA-ES, enforcing the invariance of the approach with respect to monotonous transformations of the fitness function. Whereas the choice of the SVM kernel is known to be a critical issue, the proposed approach uses the Covariance Matrix adapted by CMA-ES wit...

Two obese patients with sleep apnea syndrome were administered chlormadinone acetate (CMA), a synthetic progesterone, known as a potent respiratory stimulant to augment load compensation response as well as CO2 chemosensitivity. Before CMA administration, both cases showed normal chemosensitivity of hypoxic and hypercapnic ventilatory responses (HVR and HCVR) at daytime, although marked oxygen ...

Based on evolutionary computation techniques, we present a parallel, globally convergent, multiobjective optimization algorithm which extends the Covariance Matrix Adaptation Evolutionary Strategy (CMA-ES). This approach enables identifying multiple global optima and multiple discontinuous Pareto set solutions of the optimization problem in a compact search space. After evaluating the algorithm...

In this study, we consider simulation-based worst-case optimization problems with continuous design variables and a finite scenario set. To reduce the number of simulations required increase restarts for better local optimum solutions, propose new approach referred to as adaptive subset selection (AS3). The proposed subsamples support construct objective function in given neighborhood, introduc...

Type-I collagen self-assembles into a fibrillar gel at physiological temperature and pH to provide a cell-adhesive, supportive, structural network. As such, it is an attractive, popular scaffold for in vitro evaluations of cellular behavior and for tissue engineering applications. In this study, type-I collagen is modified to introduce methacrylate groups on the free amines of the lysine residu...

The constant modulus algorithm (CMA) is an e ective technique for blind receiver design in practice. Treating CMA as a linear estimation problem, e ects of noise and channel conditions are investigated. For the class of channels with arbitary nite impulse responses, an analytical description of locations of constant modulus receivers and an upper bound of their mean squared errors (MSE) are der...

Bayesian model averaging (BMA) weights the inferences produced by a set of competing models, using as weights the models posterior probabilities. An open problem of BMA is how to set the prior probability of the models. Credal model averaging (CMA) is a credal ensemble of Bayesian models, which generalizes BMA by substituting the single prior over the models by a set of priors. The base models ...