We have undertaken a prospective study in patients with a fracture of the femoral shaft requiring intramedullary nailing to test the hypothesis that the femoral canal could be a potential source of the second hit phenomenon. We determined the local femoral intramedullary and peripheral release of interleukin-6 (IL-6) after fracture and subsequent intramedullary reaming. In all patients, the fra...

Aim. To evaluate the clinical use of blocking screws as a supplement to stability in distal tibial metaphyseal fractures treated with statically locked intramedullary nail. Main Outcome Measurement. Alignment and reduction preoperatively, postoperatively, and at healing were the main outcome measured with an emphasis on maintenance of initial reduction on followup. Patients and Methods. This wa...

BACKGROUND This prospective study aimed to compare clinical effects of intramedullary nailing guided by digital and conventional technologies in treatment of tibial fractures. MATERIAL AND METHODS Thirty-two patients (mean age 43 years, 18 males and 14 females) who were treated for tibial fractures from October 2010 to October 2012 were enrolled. They were sequentially randomized to receive int...

BACKGROUND Approximately 2 million patients in the United States annually undergo total joint arthroplasty with reaming and placement of intramedullary nails, resulting in extravasation of bone marrow and fat into the circulatory system and potentially causing fat embolism syndrome. Acute and chronic changes in mental status documented after these procedures may be related to embolic events. Th...

BACKGROUND Metastatic disease to the shoulder girdle is a challenging problem because of the potential for pain, pathologic fracture and loss of function of that limb. Management of the bone disease centers around palliation, prevention of further complications and the preservation of residual function. A variety of surgical options exist for managing metastatic disease to the shoulder girdle a...

PURPOSE To enhance bone healing through controlled interfragmentary movements, numerous experiments have been conducted in animal models employing external fixation devices to apply mechanical stimulation to the fracture site. However, the efficacy of these fixators has been questioned. On the other hand, intramedullary nailing is a widely established clinical practice for reducing closed tibia...

A 23-year-old man was riding his motor bike on a wet country road. Negotiating a sharp curve the bike slipped and he landed on his outstretched left hand while the bike toppled over him, trapping the left leg underneath. On examination there was an obvious deformity of his left leg with swelling and bruising over the left shoulder along with some friction burns. Radiographs revealed a closed, d...

Background: Treatment of humeral shaft fractures continues to evolve as advances are made in both non-operative and operative management. The encouraging results that have been reported with recent advances in internal fixation techniques and instrumentation. The controversy still exist between plating and intramedullary nailing. MIPO (Minimal invasive plate osteosynthesis) has emerged as a new...

conclusions we advocate that unream nailing in traumatic femoral shaft fractures is a simple, safe and effective procedure with significant advantages, especially in multitrauma patients. patients and methods between january 2008 and august 2009, 50 patients with femoral shaft fractures were treated with unreamed or reamed femoral nails in our clinic. from this prospective single centre study, ...