background: in patients with anovulatory infertility the first choice of treatment for ovulation induction is an antiestrogen, most commonly clomiphene citrate (cc). however, 20-25% of the women are resistant to cc and do not ovulate perhaps due to antiestrogenic mechanism of the cc action, which involves long-lasting estrogen receptor (er) depletion. objective: the objective of the study was t...

Metformin in therapy naı¨ve patients with polycystic ovary syndrome Sir, We have read with great interest the paper by Moll et al. (2007) recently published on Human Reproduction Update. The aim of this systematic review was to assess the efficacy of metformin administration in the total spectrum of treatment possibilities for polycystic ovary syndrome (PCOS) patients in terms of fertility impr...

OBJECTIVE The objective of this study is to develop and characterize in situ thermosensitive gels for the vaginal administration of sildenafil as a potential treatment of endometrial thinning occurring as a result of using clomiphene citrate for ovulation induction in women with type II eugonadotrophic anovulation. While sildenafil has shown promising results in the treatment of infertility in ...

clomiphene critrate is an effective and safe treatment for anovulation, but in some cases resistance occurs. to evaluate the efficacy of dexamethasone in resistant anovulatory normal dehydroepiandrosterone patients, we prospectively studied 57 infertile resistant anovulatory women. each woman received 100 mg daily clomiphene critrate from cycle days 3-7 and 0.5 mg dexamethasone from cycle days ...

objective: since there is still controversy regarding the best first-line choice for ovulation induction (oi) other than clomiphene citrate (cc) in infertile women diagnosed with polycystic ovary syndrome (pcos), the aim of the present study was to compare recombinant human fsh with cc as the first course of oi in these women. materials and methods: in this pilot randomized controlled trial, 10...

background: heterotopic abdominal pregnancy is a rare entity which poses unique management challenges. case: a 24-year-old gravida 1 woman with history of two years infertility and treatment with clomiphene citrate presented with acute right lower quadrant abdominal pain. heterotopic abdominal pregnancy was recognized at 16 weeks gestation by transvaginal ultrasound scan. we aimed to remove ect...