OBJECTIVE To identify factors associated with client perceptions of the quality of primary care services in Afghanistan. DESIGN Cross-sectional survey of outpatient health facilities, health workers, patients and caretakers. SETTING Primary health care facilities in every province of Afghanistan. Main outcome measure Numerical scale of client perceptions of service quality. RESULTS Client...

Heat shock cognate protein 70 (Hsc70) regulates protein homeostasis through its reversible interactions with client proteins. Hsc70 has two major domains: a nucleotide-binding domain (NBD), that hydrolyzes ATP, and a substrate-binding domain (SBD), where clients are bound. Members of the BAG family of co-chaperones, including Bag1 and Bag3, are known to accelerate release of both ADP and client...

Academic interest in the ethical quality of accountants’ judgments has produced a steady stream of research addressing the role of education in fostering ethical behavior. Although various studies have evaluated the cognitive moral development of accounting students, few studies have considered the influence of accounting contextual factors on ethical judgments. This study evaluates the influen...

In the mining industry, at the beginning of development of a project, a consultant is assigned to build a design feasibility study to incorporate the client requirement, government regulation, and other inputs into the design. The consultant usually faces overwhelmed stages due to changes caused by the client and other stakeholders and has to repeat the process of inputting requirements into th...

Abstract. The potential for physical flora collections to support scientific research is being enhanced by rapid development of digital databases that represent characteristics of the physical specimens held in those collections and make this information available remotely. One example is the unified database of California flora observations from the Consortium of California Herbaria that was d...

When a protein misfolds in the endoplasmic reticulum (ER), it retrotranslocates to the cytosol and is degraded by the proteasome via a pathway called ER-associated degradation (ERAD). To initiate ERAD, ADP-BiP is often recruited to the misfolded client, rendering it soluble and translocation competent. How the misfolded client is subsequently released from BiP so that it undergoes retrotransloc...