Primary cutaneous lymphomas, which are diagnosed with only skin involvement, can be of B or T cell origin. Due to their varied origin as well diverse presentations, these groups have been divided further into more descriptive and representative groups. The subtypes primary marginal zone lymphoma (PCMZL), follicle center (PCFCL), diffuse large lymphoma, leg type (PCDLBCL-LT) intravascular B-cell...

Background Safflor yellow (SY) is a water-capacitive component of dried flowers, mainly from safflor in the safflower family, which contains large amount bruthin A, or A (SYA) for short. Studies have reported protective effects SYA against oxidative stress injury nerve cells. Materials and Methods In this study, H 2 O -treated PC12 cells were used as experimental materials to explore how plays ...

colorectal lymphoma is an extremely rare disease, representing less than 0.5% of all primary colorectal neoplasms. the disease is usually diagnosed in the advanced stages because of its primary non-specific symptoms. the most common involved site is cecum followed by rectum and ascending colon. diffuse large b-cell lymphoma is a more frequent subtype. although surgical resection is often techni...

The clinical and biological significance of programmed death-1 (PD-1) expression by B-lymphoma cells is largely unknown. Here, using multicolor immunofluorescent staining (MC-IF), we investigated PD-1 PD-L1 in PAX5+ (B-lymphoma), CD68+ (macrophage), or CD3+ (T-cell) formalin-fixed, paraffin-embedded samples 32 consecutive patients with de novo diffuse large B-cell lymphoma (DLBCL) treated ritux...

Human low-grade B-cell lymphoma cells cannot be readily maintained in long-term tissue culture. In an effort to obtain low-grade B-cell lymphoma cell lines for in vitro study, we used Epstein-Barr virus (EBV) as a transforming agent. T-cells were removed prior to EBV transfor mation by rosetting with sheep erythrocytes, followed by treatment with anti-Tl 1 monoclonal antibody plus complement. T...

Human low-grade B-cell lymphoma cells cannot be readily maintained in long-term tissue culture. In an effort to obtain low-grade B-cell lymphoma cell lines for in vitro study, we used Epstein-Barr virus (EBV) as a transforming agent. T-cells were removed prior to EBV transformation by rosetting with sheep erythrocytes, followed by treatment with anti-T11 monoclonal antibody plus complement. The...

Paeoniflorin (PF), extracted from the peony root, has been proved to possess antineoplastic activity in different cancer cell lines. However, it remains unclear whether PF has an antineoplastic effect against osteosarcoma cells. The present study investigated the effects and the specific mechanism of PF on various human osteosarcoma cell lines. Using the multiple methods to detect the activity ...

Diffuse Large B-Cell Lymphoma is characterized by the infiltration of small vessels lymphoid cells. These cells are not seen in systemic circulation. Depending on involvement location, it may present with different clinics such as central nervous system and skin involvement. Therefore, diagnosis delay. Diagnosis based pathology. Herein we a rare patient who initially presented cellulitis was ul...

Clonal chromosomal abnormalities were found in tumor tissue of 43 (84%) of 51 patients with non-Hodgkin's lymphoma (B-cell, 32; T-cell, 15) from an adult T-cell leukemia/I) mphoma-nonendemic area in western mainland Japan. Four tumors were tetraploid, and the other 39 had a chromosome number in the diploid range. Trisomies 3, 5, 7, 18, and \. monosomy 13, and loss of an X in female and a Y in m...