OBJECTIVE Previous studies on the association between migraine and the risk of developing hemorrhagic stroke (HS) have generated inconsistent results. The aim of the present population-based, age- and sex- matched follow-up study was to investigate whether migraine is associated with an increased risk of HS. METHOD A total of 20925 persons with at least two ambulatory visits in 2001 with the ...

The underlying mechanism of migraine and pain has been unraveled recently with the advent of neuroimaging. In this article mechanism of migraine aura and the pain of migraine are discussed. In addition, interictal studies demonstrating hyperexcitability in migraine are reviewed.

Studies of migraine with aura (MA) have shown familial aggregation of the disorder, which cannot be explained by simple mendelian inheritance. The interest in a genetic basis for the disorder has increased after identification of three genetic loci for familial hemiplegic migraine (FHM), which is a rare subtype of MA with autosomal dominant inheritance. Both genetic and environmental factors se...

INTRODUCTION CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), the most common inherited cause of stroke and dementia in adults, has been described in six Greek families. Common presenting manifestations include migraine with aura, brain ischemia, mood disorders and cognitive decline. Spontaneous intracerebral hemorrhage (SICH) rarely occurs i...

Rimegepant (Vydura) is an oral CGRP inhibitor for the treatment of acute migraine and prevention episodic migraine. This article discusses its indications, dosing clinical trial outcomes.

• Vol 9 • January 2007 46 Exercise-induced vision disturbances are uncommon. Most reports in the literature describe patients with either a vascular or demyelinating disorder. Uhthoff’s phenomenon is a classic example, commonly described in patients with multiple sclerosis. In 1971, Fisher [1] reported a 56 year old man who experienced episodes of bilateral altitudinal visual loss induced by ru...

Posttraumatic migraine may represent an important subtype of headache among the traumatic brain injury (TBI) population and is associated with increased recovery times. However, it is underdiagnosed in patients with mild traumatic brain injury (mTBI). This study examined the effectiveness of the self-administered Nine-Item Screener (Nine-Item Screener-SA), the Headache Impact Test- 6 (HIT-6), t...