© 2017 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow A 70‐year‐old man presented with an itchy eczematous well‐defined plaque of size 10 × 7 cm involving the pubic region, penis, and scrotum. It was eroded at places and covered with grayish‐white scales and crusts [Figure 1]. The lesion had persisted almost unchanged for 15 years despite treatment. Skin biopsy stained ...

UNLABELLED Colorectal cancer most commonly metastasizes to the liver and lung. Metastatic colon carcinoma (MCC) to the breast is extremely rare. Krukenberg tumor is an uncommon metastatic tumor of the ovary. CASE PRESENTATION A 38 years woman presented with abdominal pain. In evaluation colon cancer was diagnosed at stage 3. FOLFOX chemotherapy was done. After one year she developed Krukenber...

Barrett’s adenocarcinoma (BA) has seen a rapid increase in incidence throughout the Western world. The diagnosis of BA is often at an advanced stage and is generally associated with a poor prognosis and a mean survival of less than one year. Adenocarcinomas however do not arise de novo but follow an established sequence from Barrett’s metaplasia (BM) through dysplasia to neoplasia. EVorts to in...

The immunohistochemistry study made on 30 cases of salivary glands pleomorphic adenomas aims to establish the antigen profile of luminal epithelial neoplastic component proliferates into these tumors. We ascertain that luminal epithelial neoplastic cell were almost exclusively positive to antibody peculiar to epithelial differentiation (AE1/AE3, MNF 116, CK 8, CK 19, CK20, EMA) and occasional t...

Morular metaplasia has been exceptionally described in the stomach. We report the formation of morules in a case of sporadic fundic gland polyposis with low grade dysplasia in a 47 year old woman that underwent total gastrectomy. The immunophenotype of the morules was CD10, CDX2, Beta-catenin nuclear positive; p63, Ki67, chromogranin, synaptophysin, Ck20 negative. The presence of morules in a n...

Barrett’s adenocarcinoma (BA) has seen a rapid increase in incidence throughout the Western world. The diagnosis of BA is often at an advanced stage and is generally associated with a poor prognosis and a mean survival of less than one year. Adenocarcinomas however do not arise de novo but follow an established sequence from Barrett’s metaplasia (BM) through dysplasia to neoplasia. EVorts to in...

BACKGROUND Colorectal cancer is an important disease with a large morbidity and mortality and also with increasing health care costs because of widespread of the multi-modal therapy and of the new drugs that continue to appear. There are 678.000 colorectal cancer cases and 400.000 deaths from the disease worldwide. It is the second commonest cause of cancer death in the European Union but, unli...

Gastrointestinal endometriosis-associated malignancies are rare and diagnostically challenging. Mullerian endometrioid adenocarcinoma is the most common and likely to be confused with a primary colonic adenocarcinoma due to their overlapping histological features. We present a case of mullerian endometrioid adenocarcinoma arising from colonic endometriosis in a 61year-old woman who presented wi...

BACKGROUND Primary adenocarcinoma of thymus is extremely rare. CASE PRESENTATION This is a case of primary adenocarcinoma with intestinal differentiation and focal mucin production in the thymus. Thymic cyst was associated with this tumor. Intestinal differentiation was confirmed by immunohistochemical stain with positivity for CDX-2, CK20, villin, MOC31 and focal positivity of CK7. Array com...