PURPOSE To review the physiology of cardiac output regulation by the peripheral vasculature. This will enable the clinician to understand and manage the complex circulatory changes in various forms of shock, and in other common altered circulatory states encountered in anaesthetic practice. SOURCE Articles were obtained from a Medline review (1966 to present; search terms: shock, venous retur...

INTRODUCTION The aim of our study was to evaluate the efficacy and safety of deep hypothermic circulatory arrest (DHCA) as a method of cerebral protection during aortic surgery. MATERIALS AND METHODS We carried out a retrospective review of 59 consecutive patients (48 men, 11 women) undergoing elective or emergency aortic surgery requiring DHCA from January 1999 to April 2002 in 2 tertiary ca...

The paper presents a hybrid (hydro-numerical) circulatory model built to be used as a complementary tool for clinical purposes. It was developed at the Institute of Biocybernetics and Biomedical Engineering – Polish Academy of Sciences (Poland) in co-operation with the Institute of Clinical Physiology – National Council of Research (Italy). Main advantages of the model are: 1) high accuracy and...

The cardiovascular system is a central topic in physiology classes, yet it is difficult to provide undergraduates with quality laboratory experiences in this area. Thus a model circulatory system was developed to give students hands-on experience with cardiovascular fluid dynamics. This model system can be constructed from readily available materials at a reasonable cost. It has a realistic pre...

The paper presents examinations of human’s greater part of the circulatory system, modeled as an electric net. The similarities between human’s greater circulation and the electric model have been evolved. The analysis of the greater circulation was performed in PSPICE – an environment of electric circuits modeling. The designed model allows to analyze human’s greater circulation in physiologic...

BACKGROUND The systemic responses to burns (in particular, elevated levels of catecholamines and stress hormones) have been shown to have an impact on cardiac function for at least 3 years in children with burns. However, it is not clear if these changes lead to long-term effects on the heart. The aim of this study was to assess whether pediatric burn injury is associated with increased long-te...

1. Haas, J. A., J. P. Granger, and F. G. Knox. Effect of renal perfusion pressure on sodium reabsorption from proximal tubules of superficial and deep nephrons. Am. /. Physiol. 250 (Renal Fluid Electrolyte Physio/. 19): F425-F429, 1986. 2. Hartupee, D. A., J. C. Burnett. Jr., J. I. Mertz, and F. G. Knox. Acetylcholineinduced vasodilation without natriuresis du ring control of interstitial press...

Background . With the increased use of combination antiretroviral therapy, mortality people living with HIV has decreased significantly, which led to an increase comorbidity and secondary HIV-related pathology in both adults also children adolescents infection. The incidence infection those general population varies significantly. aim To assess frequency range chronic comorbidities perinatal Me...