The SynCardia total artificial heart (TAH) has emerged as an effective, life-saving biventricular replacement system for a wide variety of patients with end-stage heart failure. Although the clinical performance of the TAH is established, modern physiological characterization, in terms of elastance behavior and pressure-volume (PV) characterization has not been defined. Herein, we examine the T...

Background The purpose of this study was to analyze mortality trends in Bangladesh from 2000 to 2008, to identify the main causes of death, and categorize them by sex and age group. Methods This study used vital registration, maternal and child health data collected from Matlab, a rural area of Bangladesh, in 2000, 2004 and 2008.The data were collected and published by Health and Demographic Su...

background: with increasing age, some changes appeared in specifications of vessels which including dimensions and elasticity in their. the changes in parameters such as resistance, inertance and compliance vessels appear and eventually changes in the environmental pulse releases are in circulation. these changes clearly appear in specification of photoplethysmogram particularly in the size and...

n engl j med 370;6 nejm.org february 6, 2014 582 are highlighted. First, we concentrate on serodiscordant couples in long-term partnerships (the target population of the HIV Prevention Trials Network 052 study); Hontelez and de Vlas simulate a generalized epidemic. Second, we focus on patients who are already identified and in care (treatment as prevention). In contrast, Hontelez and de Vlas de...

ent ways to produce Coombs serum are described with little or no attempt to define how important they are in the overall scheme of human blood and serum groups. But perhaps because this is a reference book it is more important to detail everything than to discuss those areas that the authors deem important. Some subjects, the Lewis, the I, i, and the leukocyte groups, for example, are discussed...

OBJECTIVE This study was undertaken to identify preoperative and intraoperative risk factors influencing outcome after operations requiring hypothermic circulatory arrest with selective antegrade cerebral perfusion in a single center. METHODS Between November 1999 and March 2006, a total of 501 consecutive patients (median age 64 years, range 20-86 years, 320 male) underwent aortic arch surge...

BACKGROUND Surgical treatment for aortic arch disease requiring periods of circulatory arrest is associated with a spectrum of neurological sequelae. Cerebral oximetry can non-invasively monitor patients for cerebral ischaemia even during periods of circulatory arrest. We hypothesized that cerebral desaturation during circulatory arrest could be described by a mathematical relationship that is ...

BACKGROUND The systemic responses to burns (in particular, elevated levels of catecholamines and stress hormones) have been shown to have an impact on cardiac function for at least 3 years in children with burns. However, it is not clear if these changes lead to long-term effects on the heart. The aim of this study was to assess whether pediatric burn injury is associated with increased long-te...

Introduction: Cardiovascular disease (CVD) has been well documented as the leading cause of death in the general population worldwide. Physical activity is a modifiable factor in the development and progression of CVD reducing its incidence by 42-44% and reducing mortality and hospital admissions. The presence of chronic kidney disease (CKD), and the recurrence of cumulative circulatory stress ...