Polycyclic aromatic hydrocarbons (PAHs), products from the incomplete combustion of crude oil, are pollutants present in nature. Ring hydroxylating dioxygenase enzymes able to catalyze polycyclic biodegradation process with a high degree stereo-, regio-, and enantiospecificity. In this work, we first approximation binding modes 9 PAHs aromaticity catalytic sites biphenyl or naphthalene dioxygen...

Aromatic hydrocarbons present in Iraqi national surface water were believed to be raised principally from combustion of various petroleum products, industrial processes and transport output their precipitation on water.Polycyclic aromatic (PAHs) included the priority pollutant list due toxic carcinogenic nature. The concern about contamination consequent human exposure have encouraged developme...

We compared the metabolic activation in mouse skin of the weak carcinogen 6-methylchrysene, which lacks a bay region methyl group, and the strong carcinogen 5-methylchrysene, which has a bay region methyl group. Metabolites of 6-methyl chrysene were prepared using liver homogenates and were identified by their spectral properties and by comparison to synthetic standards as dihydrodiols, hydroxy...