C pulmonary diseases, a s m a i n l y d e f i n e d b y asthma, bronchiectasis, chronic obstructive lung disease (COPD), interstitial lung disease, pulmonary hypertension etc., represent the third leading cause of death in United States and account for more than 143,382 deaths in 201148. The prevalence of chronic obstructive pulmonary disease (COPD) in India is estimated to be 31.4–57.1% over 6...

Odds of major depression have significantly increased among adults with chronic diseases. However, the diagnosis of depression is often unrecognized in China. To know the prevalence of depression in medical inpatients with different chronic diseases and to assess the level of unrecognized depression among hospitalized patients, we assessed depression in patients with cardiovascular disease, dia...

Considerable knowledge has accumulated in recent decades concerning the significance of physical activity in the treatment of a number of diseases, including diseases that do not primarily manifest as disorders of the locomotive apparatus. In this review we present the evidence for prescribing exercise therapy in the treatment of metabolic syndrome-related disorders (insulin resistance, type 2 ...

Various acute and chronic inflammatory stimuli increase the number and activity of pulmonary mucus-producing goblet cells, and goblet cell hyperplasia and excess mucus production are central to the pathogenesis of chronic pulmonary diseases. However, little is known about the transcriptional programs that regulate goblet cell differentiation. Here, we show that SAM-pointed domain-containing Ets...

Wnt signaling pathways are tightly controlled under a physiological condition, under which they play key roles in many biological functions, including cell fate specification and tissue regeneration. Increasing lines of evidence recently demonstrated that a dysregulated activation of Wnt signaling, particularly the Wnt/β-catenin signaling, was involved in the pathogenesis of chronic pulmonary d...

introduction chronic obstructive pulmonary disease (copd) is a chronic disorder with many systematic complications and one of the most important reasons for patients to require mechanical ventilation, admission in intensive care unit and prolonged mechanical ventilation. although the first attempt in separation of mechanical ventilation is failed in half of chronic obstructive pulmonary disease...

asthma and chronic obstructive pulmonary disease (copd) are highly prevalent chronic diseases in the general population. both are characterized by similar mechanisms: airway inflammation, airway obstruction, and airway hyperresponsiveness. however, the distinction between the two obstructive diseases is not always clear. multiple epidemiological studies demonstrate that in elderly people with o...

forty-five patients with chronic obstructive pulmonary disease were studied to compare the acute effects of ipratropium bromide (60 µg), salbutamol (300 µg) and placebo (3 puffs) on the forced expiratory volume in 1 sec (fev 1) and forced vital capacity (pvc). ipratropium bromide produced a significantly greater improvement than salbutamol in both fev1 and fvc at 15,60 and 180 minutes after dru...

Abstract Background One of the most widespread chronic respiratory disease with rising morbidity and death is obstructive pulmonary (COPD), resulting in enormous societal economic costs. COPD a widespread, avoidable, curable condition characterised by usual symptoms such as dyspnea, coughing, and/or sputum production. The goal this study was to use questionnaire analyse clinical, demographic, a...