Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania transmitted by insects of the genus Lutzomyia sp. or Phlebotomus sp. The main syndromes are cutaneous leishmaniasis, mucocutaneous leishmaniasis, visceral leishmaniasis (kala-azar) and post-kala-azar dermal leishmaniasis. This article reviews kidney involvement in cutaneous and visceral leishmaniasis, highlighting...

Leishmaniasis is endemic and mandatorily notifiable in Greece. Epidemiological surveillance data for leishmaniasis in Greece between 1981 and 2011 are presented. In 1998, the notification system began distinguishing between visceral and cutaneous leishmaniasis. The mean annual incidence of reported leishmaniasis cases between 1998 and 2011 was 0.36 per 100,000 population. Of a total 563 leishma...

Cells of the immune system are derived from hematopoietic stem cells (HSCs) residing in the bone marrow. HSCs become activated in response to stress, such as acute infections, which adapt the bone marrow output to the needs of the immune response. However, the impact of infection-adapted HSC activation and differentiation on the persistence of chronic infections is poorly understood. We have ex...

Leishmaniasis is a zoonotic and vector-borne infectious disease that caused by the genus Leishmania belonging to trypanosomatid family. The protozoan parasite has digenetic life cycle involving mammalian host an insect vector. Leishmaniasisis worldwide public health problem falling under neglected tropical category, with over 90 endemic countries, approximately 1 million new cases 20,000 deaths...

HIV-associated immune reconstitution disease (IRD) is the clinical presentation or deterioration of opportunistic infections that results from enhancement of pathogen-specific immune responses among patients responding to antiretroviral treatment (ART). The vast majority of reported cases of IRD have been associated with mycobacterial, chronic viral and invasive fungal infections; such cases re...

Leishmaniasis, a vector-borne disease that is caused by obligate intra-macrophage protozoa, is endemic in large areas of the tropics, subtropics and Mediterranean basin. This disease is characterized by both diversity and complexity [1], it is caused by more than 20 leishmanial species and is transmitted to humans by about 30 different species of phlebotomine sandflies [2]. Leishmaniasis consis...

Leishmaniasis is a vectorborne disease caused by parasitic protozoa of the genus Leishmania. Transmitted to humans by sand flies, the disease is endemic in 88 countries on 4 continents. In the United States, the disease is something of a medical curiosity, although some clinicians may be surprised to read that autochtho-nous cases of cutaneous leishmaniasis occur in Texas [1], that visceral dis...

The term leishmaniasis comprises of a group of diseases caused by different species of a protozoan called Leishmania. There are three main clinical forms of leishmaniasis: visceral leishmaniasis, cutaneous leishmaniasis, and mucocutaneous leishmaniasis. Exclusive involvement of the mucosa is very rare. We present a case of mucosal leishmaniasis located in the oral cavity. The only manifestation...