BACKGROUND Chronic granulomatous invasive fungal rhinosinusitis (CGIFRS) is a rare disease. The underlying immune responses that drive the development of CGIFRS, as opposed to successful pathogen clearance and controlled inflammation, are not currently known. OBJECTIVE To characterize the immune responses associated with CGIFRS. METHODS In addition to a battery of basic investigations, more...

Aim: Diagnostic accuracy of MRI for diagnosis acute invasive fungal sinusitis by taking histopathology as gold standard Study design: Cross sectional study at Radiology department, Ittefaq Hospital Lahore Duration: Six months from 23-02-2018 to 23-08-2018 A total 346 cases fulfilling inclusion & exclusion criteria were taken. All done procedure. Histopathology reports also obtained. The res...

Acute sinusitis (ARS) and chronic rhinosinusitis(CRS) is a common condition worldwide.CRS is due to the infection and inflammation of paranasal sinuses. Frequent clinical manifestations of ARS include persistent symptoms with nasal discharge or cough or both, presentation with fever accompanies purulent nasal discharge, and worsening symptoms. Complications of CRS have five stages, preseptal ce...

Objective: Rare cases of fungal balls of paranasal sinuses in children. No case has been reported in young children so far. However, allergic aspergillosis has been reported in young children. Method: A case report of 2 cases of fungal balls of paranasal sinuses in children and review of the current literature concerning fungal balls of paranasal sinuses in children are presented. Result: 2 cas...

BACKGROUND Mucormycosis is a fungal infection with the following 5 classic forms: cutaneous, pulmonary, gastrointestinal, disseminated, and rhinocerebral. The rhinocerebral form can be rapidly progressive and invasive with a high mortality rate. We present a case of a 38-year-old man with invasive mucormycosis that led to a basilar artery territory stroke. Rhinocerebral mucormycosis is an unusu...

The incidence and prevalence of fungal infections in Russia is unknown. We estimated the burden of fungal infections in Russia according to the methodology of the LIFE program (www.LIFE-worldwide.org). The total number of patients with serious and chronic mycoses in Russia in 2011 was three million. Most of these patients (2,607,494) had superficial fungal infections (recurrent vulvovaginal can...

Introduction/Objective Fungal rhinosinusitis comprises of a wide range immune-pathological responses, including invasive, chronic, granulomatous, and allergic diseases. Aim this study was to determine total number patients, their characteristics, frequency symptoms, the manner disease manifestation success therapy. Methods Study included 21 patients with diagnosis FRS made according 2012 EPOS g...

Opportunistic invasive fungal infections, in particular due to Aspergillus fumigatus, are an increasing problem in hospitalized, immunocompromised patients [1-3]. Patients at risk are those with hematologic malignancies [4,5], bone marrow or solid organ transplant recipients [6,7], patients with chronic granulomatous disease [8] and AIDS patients [9]. These patient groups have in common severe ...

INTRODUCTION Invasive aspergillosis of the paranasal sinuses is a rare disease and often misdiagnosed; however, its incidence has seen substancial growth over the past 2 decades. Definitive diagnosis of these lesions is based on histological examination and fungal culture. CASE REPORT An 81-year-old woman with a history of pain in the left maxillary region is presented. The diagnosis was inva...