Acacia concinna is abundantly available in southern Asian rainforests. The fruits of this plant were employed as cleansing agents various herbal shampoos and used an expectorant traditional treatment. pods contain acacic acid based saponins. holds the surfactant property due to presence saponins it ideal use skin transdermal preparations. However, details dermal toxicity are still not reported....

hazardous chemicals may enter the body by inhalation, ingestion, injection or dermal absorption. these exposure routes constitute the overall exposure burden on the body. most occupational exposure studies have focused on measurement of the concentration of air-borne contaminants and other possible routes of exposure are often overlooked. several studies have already highlighted the importance ...

Chronic tegumentary leishmaniasis is characterized by a scarcity of parasites in lesions and a heightened inflammatory response. Deregulated and hyperactive inflammation contributes to tissue damage and parasite persistence. The mechanisms by which immune cells are recruited to the lesion and their relationship to clinical outcomes remain elusive. We examined the expression levels of chemokines...

Persistent, poorly healing wounds are a significant clinical problem in patients who have had previous irradiation. The pathology of chronic dermal ulcers is characterised by excessive proteolytic activity which degrades the extracellular matrix (required for cell migration) and growth factors and their receptors. Interestingly, the molecular basis of radiation-induced dermal wounds is poorly u...

The U.S. Consumer Product Safety Commission (CPSC) staff developed a draft performance. standard to address the hazards associated with fires involving residential upholstered furniture. Manufacturers are likely to treat some products with flame retardant (FR) chemicals if the draft standard is adopted. The CPSC staff previously assessed the potential health risks associated with the use of FR ...