Drug-induced lupus erythematosus (DILE) refers to a condition whose clinical, histological, and immunological features are similar to those seen in idiopathic lupus erythematosus but that occurs when certain drugs are taken and resolves after their withdrawal. Over 90 drugs have been linked to DILE to date and the list is growing. Like idiopathic lupus erythematosus, DILE has systemic, subacute...

Infection with the human immunodeficiency virus (HIV) leads to a chronic disarmament of the immune system. The process is progressive, having different manifestations as the status of the immune system slowly deteriorates. Some of the most common manifestations of HIV infection are cutaneous in origin, and they can have infectious, neoplastic, or noninfectious or non-neoplastic etiologies. A br...

Dermatomyositis is a systemic, autoimmune diseasewith a variety of clinical features that often includemyositis and characteristic cutaneous findings. Asubset of patients with dermatomyositis developcutaneous ulcers, often in the setting of vasculitis orvasculopathy. We present a case of dermatomyositiswith cutaneous ulcers that show perforatingcollagenosis on histopathologic examination.Acquir...

Cutaneous leishmaniasis is acquired from the bite of an infected sand fly and can result in chronic skin lesions that develop within weeks to months after a bite. Local trauma has been implicated as a precipitating event in the development of skin lesions in patients who have been infected with Leishmania species. Here we report a case series and review the literature on patients who developed ...

The odontogenic cutaneous sinus tract on the facial and cervical skin is known to occur as a result of pulp necrosis and chronic periapical periodontitis. Sinus tracts of endodontic origin usually respond well to endodontic therapy. The present case report discusses diagnosis and successful management of an extraoral cutaneous sinus tract of odontogenic origin in relation to a mandibular rigth ...

We present a case of 70 year old man with recurrent abdominal pain for one month, which preceded the onset erythematous tender nodules over bilateral lower limbs. After full history taking and extensive investigations, he was subsequently found to have chronic pancreatitis pancreatic duct stone. Skin biopsy showed lobular panniculitis in setting high serum amylase, diagnosed panniculitis. highl...

Introduction: Cutaneous leishmaniasis (CL) is a parasitic skin infection which can be debilitating. This study was performed to determine the vascular changes in the histopathology of CL. Methods: Thirty-seven patients with CL were included in a prospective study. A 4 mm punch biopsy was obtained from the border of the lesion. After histopathologic processing and H&E staining, it was reviewed ...

A thirty-year-old patient presented with an erythematous papule on the left nostril evolving for ten months. clinical examination revealed infiltrated, erythematous, well-limited plaque a raised border, covered multiple open and closed comedones. On dermoscopy, there was background some fine telangiectasias horny plugs at follicular orifices. skin biopsy performed, revealing orthokeratotic hype...

Background: Chronic graft versus host disease (cGVHD) is a major cutaneous complication of bone marrow transplantation (BMT). Although milder forms of this process may be associated with a lower incidence of tumor recurrences, it is mandatory to develop a more efficient and less harmful therapeutic approach.Methods: This case-series study enrolled 7 patients diagnosed w...

Background: Chronic graft versus host disease (cGVHD) is a major cutaneous complication of bone marrow transplantation (BMT). Although milder forms of this process may be associated with a lower incidence of tumor recurrences, it is mandatory to develop a more efficient and less harmful therapeutic approach.Methods: This case-series study enrolled 7 patients diagnosed with chronic mucocutaneous...