Background: Lymphocytes of Fanconi anemia (FA) show an increased sensitivity to the alkylating agents such as mitomycin C (MMC), but their responses to gamma-irradiation is controversial. The extent of DNA damage in leukocytes of FA patients following irradiation and MMC treatment was studied at cellular and single chromosome level. Methods: DNA damage induced by gamma-rays and MMC was measure...

Protein tyrosine phosphatases (PTPases) regulate the tyrosine phosphorylation of target proteins in‌volved in several biological activities including cell proliferation and transformation. Protein tyrosine phosphatase E (PTPE) contains duplicated PTPase-like domains and a short extracellular region. Us‌ing the fluorescence in situ hybridization method, the gene encoding PTPE (locus symbol Ptpre...

erodium (geranaiceae) species are distributed in different habitats of iran. some species are of medicinal importance while some are well known weeds. there are no chromosome counts for erdoium species of iran. chromosome numbers are given for six taxa of erodium (geraniaceae) from iran: e. cicutarium (2n=36), e. ciconium(2n=18), e. malacoides (2n=20), e. moschatum (2n=20), e. neuradifolium (2n...

115 couples with consanguineous marriage, who had experienced reported abortions or still births either in their close relatives (3 couples) or themselves (1 couple) were exposed to genetic counseling (at the shahid akbarabadi hospital) cytogenetic studied were carried out using both conventional staining and g.t.g banding for all the cases studied. the investigation demonstrated various forms ...

objectives: this study was designed to evaluate the effectiveness of a modified floor reaction ankle foot orthosis (frafo) design on gait performance in children with cerebral palsy. methods: eight children with cerebral palsy wore a modified frafo bilaterally for six weeks. motion analysis was used to assess the immediate effectiveness of the orthosis on improving gait and also following six w...