A syndrome consisting of an apical systolic click and late systolic murmur appeared over a period of three months in a patient with acromegaly. Levels of growth hormone were highest during this interval. As a result of group D streptococcal endocarditis three months later, the patient sustained cerebral embolism and acquired free mitral regurgitation from ruptured chordae tendineae. During foll...

The mitral valve is one of the four valves of the human heart. Serving as a passive check valve, a healthy mitral valve permits the flow of oxygenated blood from the left atrium to the left ventricle while preventing backflow. This is accomplished via the mutual collision of the leaflets and the tethering forces of the chordae tendineae (Figure 1). When backflow occurs, the preferred method of ...

Two cases of mitral insufficiency are reported. In 1 case the lesion was produced by rupture of the chordae tendineae of the posterior leaflet of the mitral valve. In the other case it was produced by fibrous adhesion of the posterior leaflet of the mitral valve to the underlying left ventricular wall, which occurred during healing of subacute bacterial endocarditis. Changes occurred in the pul...

Since lingual nerves may be transected during a variety of oral surgical procedures, including third molar removal, we have investigated two possible methods of repair. Quantitative morphological observations were made on feline chorda tympani and lingual nerves proximal and distal to transection injuries repaired either by epineurial suturing or by insertion of the cut ends into a perforated s...

Chordal replacement with expanded polytetrafluoroethylene (ePTFE) sutures has proven to be a simple, versatile, and durable technique for the treatment of prolapsed cusps causing mitral valve regurgitation. ePTFE is known for its strong resistance to tension, and is judged to be unbreakable under physiological conditions. Herein are reported two cases of rupture of synthetic chordae tendineae; ...

A rare type of congenital mitral regurgitation is presented for the first time as an isolated cardiac anomaly. The malformation consists of a particular arrangement of the chordae tendineae of the posterior leaflet: the chordae, leaving the free margin or the undersurface, insert into the latter once again. A definition of the anomaly and a classification of all the chordal anomaliesfound in co...

A spectrum of mitral valve disease was noted in 71 per cent of 163 specimens with transposition of the great arteries. At one end of the spectrum were hearts with normal mitral valve, except that the free margin of the anterior leaflet was shortened; at the other end were specimens with underdevelopment of the space between or behind the papillary muscles of the left ventricle. In additional ...

Background: Primary intra cardiac tumors are rare. In this article, we present papillary fibroelastoma of mitral valve chordae. Case Presentation: A 35-year old man presented with atypical chest pain and palpitation. Physical examination and electrocardiogram were normal. Transesophageal echocardiography (TEE) revealed a mass of 1015 mm attached to chordae of anteromedial papillary muscle of ...