Angiogenesis and vasculogenesis constitute two processes in the formation of new blood vessels and are essential for progression of solid tumors. Consequently, targeting angiogenesis, and to a lesser extent vasculogenesis, has become a major focus in cancer drug development. Angiogenesis inhibitors are now being tested in pediatric populations whereas inhibitors of vasculogenesis are in an earl...

We reviewed the published literature on the relationship between childhood cancer and fetal alcohol spectrum disorders (FASD). A Pub Med search identified 12 subjects with the co-occurrence of FASD and cancer. We included an additional case from the author's institution. Neuroblastomas comprised 6 of the 13 (46%) case reports, yet neuroblastomas comprise only about 10% of childhood cancers (z =...

Childhood cancer has been a growing problem in the United States with approximately 8,000 new cases reported annually for children under the age of 15. The first step in epidemiological studies of childhood cancer is usually to identify places with elevated rates. Past research placed particular emphasis on childhood cancer in children living near nuclear facilities. This study tests whether st...

background: a number of randomized trial studies and longitudinal researches emphasize that despite problems in social adjustment and cognitive damages, children with cancer demonstrate good emotional adjustment. methods: most of the research findings in this area are obtained using objective tools such as questionnaires. “vitality of children”, as a drawing tool, was used as a basis to draw a ...

OBJECTIVE To examine the relation between energy intake in childhood and adult mortality from cancer. STUDY DESIGN Cohort study. SETTING 16 rural and urban centres in England and Scotland. SUBJECTS 3834 people who took part in Lord Boyd Orr's Carnegie survey of family diet and health in prewar Britain between 1937 and 1939 who were followed up with the NHS, central register. Standardised ...

BACKGROUND International studies examining the association between the incidence of childhood cancer and characteristics of the area in which the patient lives have generally reported inconsistent patterns. Area-based differentials in childhood cancer throughout Australia have not been previously published at a national level. PROCEDURE Population-based information from the Australian Paediat...

Brief summary: This prospective cohort study leveraged data from the International Childhood Cardiovascular Cohorts (i3C) Consortium, including 42 324 participants at baseline and followed-up over a mean of 35 years, in order to investigate associations between cardiovascular risk factors (CVRF, body-mass index, systolic blood pressure, total cholesterol levels, triglycerides, smoking) childhoo...

abstract background: childhood leukemia, the most common type of cancer in children and teens, is a cancer of the white blood cells. as antioxidants can promote immune system against all types of cancer, the aim of this study was to explore the metabolic regulation and anti-oxidative effect of sesquiterpen-rich extract of ferula asafoetida (fa) on children with leukemia. materials and methods: ...