Three methods are presented for simultaneous determination of ibuprofen and paracetamol without previous separation. The first method depends on first derivative UV spectrophotometry, with zero-crossing measurement. The first derivative amplitudes at 230 and 290 nm were selected for the assay of ibuprofen and paracetamol, respectively. The second method depends on first derivative of the ratio-...

In this study, the NIR and UV-Vis spectroscopy methods, which are frequently used in pharmaceutical industry, were applied to environments where Paracetamol, Propyphenazone Caffeine active substances present, spectroscopic data obtained evaluated comparatively with ICA-ANN PLS-1, powerful chemometric methods. When using solid agents method, liquid solutions equivalent them method. Following app...

Visible spectra of cold stored, cooked, and diseased chicken meats were collected. Changes in ratios of R(1)=A(485 nm)/A(560 nm) and R(2)=A(635 nm)/A(560 nm,) which are related to absorbances of the bands at 485 (metmyoglobin), 560 (oxymyoglobin), and 635 nm (sulfmyoglobin), were observed to be useful for studying the variation of meat color under the conditions of cold storage and cooking proc...

The significant spectral overlap (Di) 0.5 = 0.5667 which is about 75.3% overlapping of the UV/Visible absorption spectra of iron (II) and copper (II) complexes necessitates chemometric assisted methods for simultaneous analysis of these ions in the pharmaceutical mixture. These metal ions were analyzed simultaneously by UV/Visible spectrophotometric method where 8-hydroxyquinoline was used as a...

Purpose: To study the effect of some factors on the size of finasteride nano-emulsion by chemometric approach which could predict the size of nano-emulsion droplets under different conditions. Methods: Nano-emulsions were prepared using spontaneous emulsification method which occurs when organic and aqueous phases are mixed. The organic phase was a homogeneous solution of oil (finasteride as a ...

In this paper we investigate the usage of non-linear chemometric models, which are calibrated based on near infrared (FTNIR) spectra, in order to increase efficiency and to improve quantification quality in melamine resin production. They rely on fuzzy systems model architecture and are able to incrementally adapt themselves during the on-line process, resolving dynamic process changes, which m...

Cassava roots are an important source of dietary and industrial carbohydrates and suffer markedly from postharvest physiological deterioration (PPD). This paper deals with metabolomics combined with chemometric tools for screening the chemical and enzymatic composition in several genotypes of cassava roots during PPD. Metabolome analyses showed increases in carotenoids, flavonoids, anthocyanins...

The present work deals with the chemometric modeling of antioxidant molecules belonging to the class of flavone derivatives employing the quantitative structure-activity relationship (QSAR) technique. A QSAR model was initially built based on the Fujita-Ban method with the training set molecules. Due to the inability of the Fujita-Ban type model to predict satisfactorily the activity of the tes...

The wine is one of the most consumed drinks over the world, being subjected to falsification or adulteration regarding the variety, vintage, and geographical region. In this study, the influence of different characteristics of wines (type, production year, and origin) on the total phenolic content, total flavonoids content, antioxidant activity, total sugars content, pH, and 18O/16O isotopic ra...