More than 20 novel classes of antibiotics were produced between 1930 and 1962. Since then, only four new classes of antibiotics were marketed. Interestingly, none of these new classes is really novel: daptomycin, approved in 2000, was discovered in the early 1980s; linezolid, approved in 2000, derives from a synthetic lead discovered in the 1970s; pleuromutilins, approved in 2007, have been wid...

For studying both hydrogen bond and dipole-dipole interactions between methanol molecules (self-association) the geometry of clusters of increasing numbers of methanol molecules (n = 1,2,3) were optimized and also their vibrational frequencies were calculated with quantum chemical methods. Beside these B3LYP/6-311G** calculations, PCM calculations were also done for all systems with PCM at the ...

the history of medicine as the history of medical science and the history of medicine as a chapter in the struggle for social emancipation. The book concludes with a most useful bibliography of the history of Canadian medicine which demonstrates that the condition of the study is not quite as desperate as Dr. Shortt has indicated. In any case, he and his contributors are to be congratulated on ...

abstract islamic medicine is regarded as a comprehensive medical school with a long, glorious and worldwide reputation. some of the physicians of this school are famous worldwide and have contributed valuable services to the scientific world. given the dramatically increasing prevalence of cancer and the relative inefficacy of current medications, there is a great demand for the introduction of...

evidence based medicine (ebm) is a new approach to patient management which incorporates best evidence with the clinical expertise of the health care providers. although this approach has had a rapid growth in many clinical disciplines, its applications in radiology and nuclear medicine has not been addressed sufficiently. in this review ebm is briefly explained and the first two steps of the e...

The interface between nanosystems and biosystems is emerging as one of the broadest and most dynamic areas of science and technology, bringing together biology, chemistry, physics and many areas of engineering, biotechnology and medicine. The combination of these diverse areas of research promises to yield revolutionary advances in healthcare, medicine and the life sciences through, for example...

archaeological excavations have revealed diverse medical materials of the bronze, neolithic, hellenistic ages, the roman empire and late ancient culture period in the territory of georgia. these materials are rich repositories of national, spiritual and material culture kept in different museums of georgia. to show the origin and development of medicine in georgia, it is, primarily, crucial to ...

results the result of the present study confirmed wide use of herbal drugs use during pregnancy that need to report the safety concerns of these drugs during pregnancy. background investigations across the world confirm dramatic increment in the use of complementary and alternative medicine in pregnant women. the most important aspect is lack of awareness of pregnant women about potential effec...

Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN, USA Quantitative Systems Biology Center, Vanderbilt University School of Medicine, Nashville, TN, USA Department of Informatics, Systems and Communication, University of Milano-Bicocca, Milan, Italy SYSBIO.IT Centre of Systems Biology, Milan, Italy Chemical and Physical Biology Graduate Program, Vanderbilt Un...

1Heart Failure Bioscience Department, Cardiovascular and Metabolic Diseases (CVMD), Innovative Medicines & Early Development (IMED) Biotech Unit, AstraZeneca R&D, 43150 Mölndal, Sweden 2Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences, Faculty of Medicine, University of Chile, 8380492 Santiago, Chile 3Department of Internal Medicine, Cardiology Divi...