نتایج جستجو برای: chemical evaluation

تعداد نتایج: 1184716  

Journal: :Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement 1980
M Danz H Urban

Growth stimulating influences such as partial hepatectomy, chemical promoters and various carcinogens act mitogenically on the adrenal cortex of rats. The proliferative response of this 'non-target' tissue is probably due to systemically operating mechanisms which are independent of the organotropism of a substance. Therefore, this in vivo test appears useful for short-term evaluation of the pr...

2009
Mihai Lupu Florina Piroi Xiangji Huang Jianhan Zhu John Tait

TREC 2009 was the first year of the Chemical IR Track, which focuses on evaluation of search techniques for discovery of digitally stored information on chemical patents and academic journal articles. The track included two tasks: Prior Art (PA) and Technical Survey (TS) tasks. This paper describes how we designed the two tasks and presents the official results of eight participating groups.

2003
Paul E.M. Phillips R. Mark Wightman

Microsensors are miniaturized analytical devices for making in-situ chemical measurements in biological systems with extraordinary temporal resolution. Their most severe limitation is chemical selectivity. Here, we suggest guidelines that can be applied to a range of in-vivo microsensor applications for evaluation of analyte identification and improvement of selectivity. # 2003 Published by Els...

2011
Pamela Reed Gibson Amanda Lindberg

Ninety physicians practicing in the state of Virginia USA completed a mail survey regarding Multiple Chemical Sensitivity (MCS). Survey questions addressed demographics; familiarity with MCS; etiology; overlapping conditions; accommodations made for patients and practices regarding evaluation, treatment, and referral. A little over half of respondents were familiar with MCS. Under a third had r...

2017
Zhuo Yang Junjie Ba Jing Pan Jianfeng Luo Jianlan Guo

Hazardous chemical is the chemical product in chemical industry. Hazardous chemicals are often toxic. Some hazardous chemicals are corrosive, or easily lead to explosion. In the process of production, storage and transportation, hazardous chemicals can easily lead to leakage or explosion accidents. These result in a large number of casualties and damage to the surrounding environment. Logistics...

2010
Patrick Baum Ramona Schmid Carina Ittrich Werner Rust Katrin Fundel-Clemens Susanne Siewert Martin Baur Lisa Mara Lore Gruenbaum Armin Heckel Roland Eils Roland E. Kontermann Gerald J. Roth Florian Gantner Andreas Schnapp John E. Park Andreas Weith Karsten Quast Detlev Mennerich

A phenocopy is defined as an environmentally induced phenotype of one individual which is identical to the genotype-determined phenotype of another individual. The phenocopy phenomenon has been translated to the drug discovery process as phenotypes produced by the treatment of biological systems with new chemical entities (NCE) may resemble environmentally induced phenotypic modifications. Vari...

2005
Nicholas A. Allen

The cell is a highly ordered and intricate machine within which a wide variety of chemical processes take place. The full scientific understanding of cellular physiology requires accurate mathematical models that depict the temporal dynamics of these chemical processes. Modelers build mathematical models of chemical processes primarily from systems of differential equations. Although developing...

2015
Bong-In Choi Byung-Taek Ryu Suk-Hyun Na Seon-Yong Chung

OBJECTIVES In this study, the possibility of using existing test data provided in Korea and elsewhere for the registration of chemical substances was examined. Data on 510 chemical substances that are among the first subject to registration under the "Act on the Registration and Evaluation, etc. of Chemical Substances (K-REACH)" were analyzed. METHODS The possibility of using existing data fr...

2015
Natalie Fey

Descriptors calculated from molecular structures have been used to map different areas of chemical space. A number of applications for such maps can be identified, ranging from the fine-tuning and optimisation of catalytic activity and compound properties to virtual screening of novel compounds, as well as the exhaustive exploration of large areas of chemical space by automated combinatorial bu...

2002
Kengo Sudo Masaaki Takahashi Jun-ichi Kurokawa Hajime Akimoto

We present a new global three-dimensional chemical model for the troposphere, named CHASER (CHemical AGCM for Study of atmospheric Environment and Radiative forcing). This model, developed in the framework of Center for Climate System Research/National Institute for Environment Studies (CCSR/NIES) atmospheric general circulation model (AGCM), is aimed to study tropospheric photochemistry and it...

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