The interference of antibodies to factor VIII coagulant protein (Vlll:C) of 9 nonhemophilic patients with the binding to factor VIII coagulant antigen (VIII:CAg) of a reference hemophilic ‘251-Fab’ reagent, used in a liquid phase Vlll:CAg assay, was studied. The binding competition was estimated from immunoradiometric assay (IRMA) doseresponse slope of Vlll:CAg present in patient plasma. interf...

This paper reports on the application of Artificial Neural Network techniques to coagulation control in drinking water treatment plants. The coagulation process involves many complex physical and chemical phenomena which are difficult to model using traditional methods. The amount of coagulant ensuring optimal treatment efficiency has been shown experimentally to be non-linearly correlated to r...

Enzymes involved in the coagulation process have received great attention as potential targets for the development of oral anti-coagulants. Among these enzymes, coagulation factor Xa (FXa) has remained the center of attention in the last decade. In this study, 16 ginsenosides and two sapogenins were isolated, identified and quantified. To determine the inhibitory potential on FXa, the chromogen...

The Badaksinga Drinking Water Processing Installation is an installation owned by Perumda Tirtawening Water, Bandung City, has 2 of these installations, the first which a design from Degremont - France, built around 1954 with capacity 1000 liters/second. second IWACO-Dutch flow rate 800 raw water for two installations comes Cisangkuy River and Cikapundung River. To purify water, PAC (Poly Alumi...

Blood coagulation could be recognized as intrinsic inflammation. The coagulant mediators (FVIIa, FXa, thrombin (FIIa), FXIIa) and fibrin(ogen) activate cellular signaling, eliciting the production of cytokines, chemokines, growth factors, and other proinflammatory mediators. Hypercoagulability with elevated coagulant mediators would certainly trigger hyper-inflammatory state not to mention abou...

It is widely known that metformin reduces the levels of circulating pro-coagulant factors and improve fibrinolytic activity in type 2 diabetes when used in therapeutic doses. Potential alterations of coagulation have not been reported in patients with metformin intoxication. We evaluated certain components of the coagulation system in a patient with metformin intoxication upon admission and aft...

Slaughterhouse wastewater contains various and high amounts of organic matter (e.g., proteins, blood, fat and lard). In order to produce an effluent suitable for stream discharge, chemical coagulation and electrocoagulation techniques have been particularly explored at the laboratory pilot scale for organic compounds removal from slaughterhouse effluent. The purpose of this work was to investig...

The massive growth of potentially toxic cyanobacteria in water supply reservoirs, such as Legedadi Reservoir (Ethiopia), poses a huge burden to purification units and represents serious threat public health. In this study, we evaluated the efficiency flocculants/coagulants chitosan, Moringa oleifera seed (MOS), poly-aluminium chloride (PAC) settling cyanobacterial species present Reservoir. We ...