Background: Myenteric interneurones are involved in the reflexes that control the motility of the human colon. Aims: The distribution of choline acetyltransferase (ChAT) and nitric oxide synthase (NOS) immunoreactivity in myenteric interneurones was investigated in this study. Methods: DiI (1,1′didodecyl 3,3,3′,3′-indocarbocyanine perchlorate) was applied to the myenteric plexus of the human co...

The M-transcript of human choline acetyltransferase (ChAT) produces an 82-kDa protein (82-kDa ChAT) that concentrates in nuclei of cholinergic neurons. We assessed the effects of acute exposure to oligomeric amyloid-β1-42 (Aβ1-42) on 82-kDa ChAT disposition in SH-SY5Y neural cells, finding that acute exposure to Aβ1-42 results in increased association of 82-kDa ChAT with chromatin and formation...

OBJECTIVE The purpose of the study was to examine use of the Modified Checklist for Autism in Toddlers (M-CHAT) as an autism-specific screening instrument in a large, geographically diverse pediatrics-based sample. METHODS The M-CHAT and the M-CHAT Follow-Up (M-CHAT/F) were used to screen 18,989 toddlers at pediatric well-child visits in 2 US geographic regions. Pediatricians directly referre...

INTRODUCTION The present study assessed the efficacy of initial basal-supported oral therapy (BOT) with sitagliptin for achievement of glycemic control and subsequent switching from BOT to sitagliptin-based oral therapy. METHODS Nineteen recently diagnosed type 2 diabetic patients who had received no antidiabetic medication in the previous 2 years were sequentially examined for the 24-week st...

signature type hierarchy bot type feature1 :value1 feature2 :value2 subtype1 subtype2. theory.pl string-> preterminal. rulename rule mother ===> cat> daughter1 cat> daughter2. (trale/0) signature type_hierarchy bot s np vp .

* To Dr. T. H. Goodspeed, Professor of Botany and Director of the Botanical Garden, University of California, the author expresses her sincere gratitude both for counsel and for extending every research facility, including seeds of most of the Nicotiana cultures investigated. In addition she acknowledges with pleasure seeds sent her by E. E. Cheel, J. M. Black, Professor J. B. Cleland and Hazel...

In this work, we introduce a swarm robotic system, called a swarm-bot. A swarm-bot is a self-assembling and self-organizing artifact composed of a swarm of s-bots, mobile robots with the ability to connect to/disconnect from each other. In particular, we address the problem of synthesizing controllers for the swarm-bot using Artificial Evolution. We describe the motivation behind the choice of ...

So-called ‘social bots’ have garnered a lot of attention lately. Previous research showed that they attempted to influence political events such as the Brexit referendum and the US presidential elections. It remains, however, somewhat unclear what exactly can be understood by the term ‘social bot’. This paper addresses the need to better understand the intentions of bots on social media and to ...

Botnets have become the most powerful tool for attackers to victimize countless users across cyberspace. Previous work on botnet detection has mainly focused on identifying infected bot computers or IP addresses and not on identifying bot processes on a host machine. This paper aims to fill this gap by presenting a bot process detection technique based on process symptoms such as: TCP connectio...