OBJECTIVE To compare the impact of 1000 micrograms of self-administered vaginal misoprostol versus self-administered vaginal placebo at home on preoperative cervical ripening in both premenopausal and postmenopausal women before operative hysteroscopy. DESIGN Two separate but identical parallel, randomised, double-blind, placebo-controlled sequential trials, one in premenopausal women and one...

: Induction of labor is defined as artificially stimulating the uterus to start labor. Mifepristone a synthetic steroid hormone analog that has both anti-progesterone and anti-glucocorticoid activities. This study aimed efficacy mifepristone in induction cervical ripening. was conducted Gandhi Hospital from August 2022 November 2022. A total 100 antenatal cases were admitted for safe confinemen...

Obese women are at an increased risk of antepartum pregnancy complications and are therefore more likely to require an induction of labor than normal weight women. They also have an increased rate of failing an induction of labor, a rate that rises significantly with increasing body mass index, and subsequent surgical and neonatal complications of an intrapartum cesarean delivery. This increase...

We describe experimental observations and theoretical analysis of the coarsening of distributions of twodimensional nanoclusters, either adatom islands or vacancy pits, on metal surfaces. A detailed analyses is provided for Ag(111) and Ag(100) surfaces, although we also discuss corresponding behavior for Cu(111) and Cu(100) surfaces. The dominant kinetic pathway for coarsening can be either Ost...

OBJECTIVE This study aimed to determine the optimal Foley catheter balloon volume (30-mL vs. 80-mL) and the maximum time for cervical ripening (12 hours vs. 24 hours) to improve vaginal delivery rate within 24 hours of induction. METHODS We conducted an open-label, randomized controlled trial in a teaching hospital in China. Women with a term singleton pregnancy, cephalic presentation, intact...

This investigation was undertaken to compare the cost impact of prostaglandin E2 gel delivered intracervically in an outpatient versus an inpatient setting. Eligible pregnant women with a singleton gestation that was beyond 37 weeks gestational age and who had an unfavorable cervix (Bishop score < or = 4) received a single dose of 0.5 mg of prostaglandin E2 intracervically as an outpatient or o...

The importance of progesterone (P4) for maintenance of pregnancy, its role in cervical ripening and uterine contractions is at least partly established and therefore, not surprisingly, the basis for the concept to use P4 as a treatment for preterm birth. Due to the complexity of the condition of preterm birth there are still questions concerning the optimal population that might benefit, timing...

OBJECTIVES To compare uterine rupture, maternal and perinatal morbidity rates in women with one single previous cesarean after spontaneous onset of labor or low-dose prostaglandin-induced cervical ripening for unfavourable cervix. STUDY DESIGN This was a retrospective cohort study of 4,137 women with one single previous cesarean over a 22-year period. Inpatient prostaglandin administration co...