STUDY DESIGN The expression of cyclooxygenase-2 was studied immunohistologically in specimens from lumbar disc herniation. The cultured disc cells also were examined to evaluate the significance of cyclooxygenase-2, which might be involved in the pathogenesis of lumbar disc herniation. OBJECTIVE To investigate whether cyclooxygenase-2 might be involved in the pathogenesis of lumbar disc herni...

Of the many causes of vertebrobasilar insufficiency (VBI), extrinsic compression of the vertebral artery (VA) is relatively uncommon. A syndrome of VBI caused by extrinsic compression of the VA secondary to head rotation has been termed positional vertebrobasilar ischemia. The authors present a case of transient VBI caused by herniation of a cervical disc. Transcranial Doppler ultrasonography w...

PURPOSE Small spinal canal dimensions play a role in symptomatic adult disc herniation, but its role in adolescent disc herniation has not been investigated with MRI. The goal of this study was to examine retrospectively if there is a correlation with dimensions of osseous spinal canal and need of discectomy in an adolescent population suffering from disc herniation. METHODS A retrospective r...

Our aim was to analyse causes for persistence of pain after lumbar discectomy and outcome of reoperations. Out of 37 reoperated patients, 22 with a minimum follow-up period of one year were included in this retrospective study concerning the years 1993 to 2000. All patients had previously undergone laminotomy and discectomy and fusion was not required during second operations. Outcome was evalu...

HAS THERE BEEN PROGRESS IN THE PHYSIOPATHOLOGY OF DISC HERNIATION ASSOCIATED RADICULOPATHY? Since 1934, when a link was demonstrated between disc herniation and sciatica, it has been accepted that compression of the nerve root by disc herniation explained the sciatica. Surgical treatment therefore became standard when medical treatment failed. It now seems that ‘‘chemical’’ factors have a centr...

SUMMARY OF BACKGROUND DATA The association between the facet tropism and the development of lumbar disc herniation has been studied; however the results remain controversial. OBJECTIVE To determine the association between the facet tropism and the development of lumbar disc herniation. STUDY DESIGN A cross-sectional study. MATERIAL AND METHOD MRI of 34 patients with lumbar disc herniation...

[Purpose] To present the outcome of a patient, having sciatica and MRI-verified disc herniation/sequestration who underwent Chiropractic BioPhysics® (CBP®) protocol designed to improve the lumbar lordosis. [Subject and Methods] A 56-year-old male suffered from chronic low back pain and recent sciatica due to lumbar disc herniation despite being under continuous care from three previous chiropra...