Two patients with protein S deficiency with acquired multiple pial and dural arteriovenous fistulae (AVFs) following superior sagittal sinus (SSS) thrombosis are reported. Case 1 is a 38-year-old male with protein S deficiency who developed generalized seizure due to SSS thrombosis. Local fibrinolysis was achieved in the acute stage. His 10-month follow-up angiogram revealed an asymptomatic acq...

Thromboembolic events represent the main cause of morbidity and mortality in patients with polycythemia vera. Leukocytosis has been identified as an important risk factor for development of vascular thrombosis. A 47-year-old woman with polycythemia vera presented with pain and swelling in her right calf. She was scheduled to receive anagrelide which was effective on polycythemia and thrombocyto...

Anti-NMDA receptor encephalitis is an autoimmune well- known to pediatric neurologists. The characteristic combination of symptoms and detection NMDA antibody can confirm the diagnosis. Most children respond well immunosuppressive therapy. Anti-GABAB usually occurs in adult patients. patients present clinically with limbic encephalitis. Cases are rare. Cerebral venous thrombosis also has a very...

The term unusual site venous thrombosis defines uncommon clinical manifestations of venous thromboembolism occurring in sites different from the lower limbs or the lungs, with peculiar pathophysiological features and clinical history. Information on long-term outcomes of unusual site thrombosis is generally scant, because most studies are small and usually retrospective. Recurrence rate of cere...

Hypercoagulability disorders are commonly encountered in clinical situations in patients with a variety of cancers. However, several hypercoagulability disorders presenting as first symptoms or signs in cancer patients have rarely been reported. We herein described a case of a woman with adenocarcinoma of the lung presenting with deep vein thrombosis, nonbacterial thrombotic endocarditis, recur...

introduction antiphospholipid syndrome (aps) associated with intra-cardiac thrombus and pulmonary embolism is infrequent. however, the presence of pleural effusion is extremely rare. case presentation a 42-year-old woman, admitted with palpitation, dyspnea and history of stroke and thrombocytopenia is described. doppler sonography revealed deep vein thrombosis. moreover, subsequent investigatio...

renal vein thrombosis (rvt) is the most frequent vascular abnormality in newborns, but rarely seen in adults. rvt is an acute problem, and diagnostic and therapeutic approaches should be done immediately. surgical thrombectomy is not a rational approach and the treatment of choice is conservative management and thrombolytic therapy. we present a 45 years old male patient with chronic renal vein...

BACKGROUND AND PURPOSE Diagnostic delay of cerebral vein and dural sinus thrombosis may have an impact on outcome. METHODS In the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) cohort (624 patients with cerebral vein and dural sinus thrombosis), we analyzed the predictors and the impact on outcome of diagnostic delay. Primary outcome was a modified Rankin Scale score ...

Evidence of damage to cerebral vein walls was sought in 70 cases of multiple sclerosis. Seventy control cases were also examined. The multiple sclerosis cases showed venous intramural fibrinoid deposition (7%), recent haemorrhages (17%), old haemorrhages revealed by haemosiderin deposition (30%), thrombosis (6%) and thickened veins (19%). In all, 41% of all multiple sclerosis cases showed some ...