Force control deficits have been repeatedly documented in autism spectrum disorder (ASD). They are associated with worse social and daily living skill impairments in patients suggesting that developing a more mechanistic understanding of the central and peripheral processes that cause them may help guide the development of treatments that improve multiple outcomes in ASD. The neuromuscular mech...

A computer-automated shape optimization methodology has been developed for the purpose of providing internal cooling systems designers the ability to optimize the internal cooling configuration, geometry and heat transfer enhancements for greater cooling efficiency and more durable turbine airfoils. The methodology presents the theory and practical programming requirements for coupling existing...

Micromachined force gauges, like many microdevices, are subject to inevitable and inherent uncertainty in dimensional and material parameters that lead to variability in the gauge accuracy and reliability. This paper presents a methodology for the design of a micromachined force gauge under uncertainty, in which the measured force and the maximum stress in the beams in the gauge are related to ...

The atomic force microscope (AFM) is a versatile, high-resolution tool used to characterize the topography and material properties of a large variety of specimens at nano-scale. The interaction of the micro-cantilever tip with the specimen causes cantilever deflections that are measured by an optical sensing mechanism and subsequently utilized to construct the sample topography. Recent years ha...

In human body movement simulation such as vertical jump by a forward dynamic model, optimal control theories must be used. In the recent years, new methods were created for solving optimization problems which they were adopted from animal behaviors and environment events such as Genetic algorithm, Particle swarm and Imperialism competitive. In this work, the skeletal model was constructed by Ne...

In the structural optimization problem, the aim is to decrease the amount of structural costs and weight, but the safety of platform should not violate the individual limits enforced by offshore codes. The outer diameter and thickness of members are two important variables in the optimization process and their final dimensions should be obtained according to the optimization algorithms such as ...

Exercise-induced muscle fatigue has been shown to be the consequence of peripheral factors that impair muscle fiber contractile mechanisms. Central factors arising within the central nervous system have also been hypothesized to induce muscle fatigue, but no direct empirical evidence that is causally associated to reduction of muscle force-generating capability has yet been reported. We develop...