نتایج جستجو برای: cellular microenvironment

تعداد نتایج: 462140  

2012
Raymond H. W. Lam Yubing Sun Weiqiang Chen Jianping Fu

Mechanotransduction is known as the cellular mechanism converting insoluble biophysical signals in the local cellular microenvironment (e.g. matrix rigidity, external mechanical forces, and fluid shear) into intracellular signalling to regulate cellular behaviours. While microfluidic technologies support a precise and independent control of soluble factors in the cellular microenvironment (e.g....

Journal: :Biotechnology journal 2015
Ty Harkness Jason D McNulty Ryan Prestil Stephanie K Seymour Tyler Klann Michael Murrell Randolph S Ashton Krishanu Saha

Understanding the mechanisms underpinning cellular responses to microenvironmental cues requires tight control not only of the complex milieu of soluble signaling factors, extracellular matrix (ECM) connections and cell-cell contacts within cell culture, but also of the biophysics of human cells. Advances in biomaterial fabrication technologies have recently facilitated detailed examination of ...

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