Glycochenodeoxycholate (GCDA), a toxic component in bile salts, is involved carcinogenesis of gastrointestinal tumors. The objective this research was to study the function ERK1/2 GCDA-mediated survival and drug-resistance hepatocellular carcinoma cells (HCCs). Firstly, extracellular signal-regulated kinase 1/2 (ERK1/2) detected extensively expressed liver cancer cells, silencing by RNA interfe...