background: camellia sinensis and zataria multiflora as the potent antioxidants and anti-inflammations are crucial in the management of wound therapy. lipopolysaccharide (lps) was used for the proliferative potential on fibroblast cells and induction of inflammatory mediators. objective: we examined the effects of lps and herbal extracts combination in order to identify their mechanisms of acti...

background: in the modern lifestyle, the increase in cancer and related chronic disorders is a major public health problem. in spite of different methods used for the treatment of these conditions, natural medicines have high demands due to their significant effects as immune enhancement and therapeutic agents and fewer side effects in comparison with other treatment methods. hence, this study ...

objective: grape virus diseases are a serious problem in iran. leaves and fruits of grape have been used for different purposes like cooking in iran. the present investigation was carried out to study on the cytotoxic-activities of extracts of fruits and leaves of vitis vinifera from both virus-free and virus-infected grape cultivars against breast cancer cell line (mda-mb-231) and human embryo...

cancers belong to a group of disorders which are very important for researchers.  because they have several types and cause mortality in human beings. many  investigations are performing in order to introduce cheaper drugs with lower side  effects especially with natural sources. ferula genus grows all over the world but  some of them are endemic to iran. many investigations have proved differe...

The present study was carried out to evaluate the cytotoxic effects of aqueous (AE) and ethanolic (EE) extracts of Artemisia herba alba on human laryngeal carcinoma (Hep-2) cell line and murine mammary adenocarcinoma (AMN-3) cell line in vitro. The in vitro cell growth assay showed that there were timeand concentration-dependant cytotoxic effects of both extracts on the tested cell lines. The r...

Whole cell extracts from human lymphoid cell lines can perform in vitro DNA repair synthesis in plasmids damaged by agents including UV or cis-diamminedichloroplatinum(II) (cis-DDP). Extracts from xeroderma pigmentosum (XP) cells are defective in repair synthesis. We have now studied in vitro DNA repair synthesis using extracts from lymphoblastoid cell lines representing four human hereditary s...

The present study investigates the antioxidant, anticancer, anticholinesterase, anti-genotoxic activities and phenolic contents of flower, fruit and seed methanol extracts of Hypericum retusum AUCHER. The amounts of protocatechuic acid, catechin, caffeic acid and syringic acid in methanol extracts were determined by HPLC. Total phenolic content of H. retusum seed extract was found more than fru...

Introduction: Chronic myeloid leukemia (CML) is a malignant clonal disorder of hematopoietic stem cells resulting in the increase of myeloid cells, erythroid cells and platelets in the peripheral blood and hyperplasia in bone marrow. The research evaluated the cytotoxic effects of hydro-alcoholic extracts of Lepidium Sativum (Cress plant) shoots before and after flowering on K562 cell line as a...

Background and objectives: Cancer is a major health problem in the world. The aim of this study was to extract the flowers of Allium austroiranicum used by Iranian people as a condiment or for its medicinal effects followed by bioassay guided fractionation of the extracts and fractions, using anti-proliferative effects against ovarian and cervical cancer cells. <strong...