objective: biomaterial technology, when combined with emerging human induced pluripotent stem cell (hipsc) technology, provides a promising strategy for patient-specific tissue engineering. in this study, we have evaluated the physical effects of collagen scaffolds fabricated at various freezing temperatures on the behavior of hipsc-derived neural progenitors (hipsc-nps). in addition, the coati...

in recent years the science of tissue engineering has emerged as a powerful tool for the development of a novel set of tissue replacement parts and technologies. recent advances in the fields of biomaterials, stem cell technologies, growth factor field and biomimetics have created a unique set of opportunities for investigators to fabricate lab-grown tissues from combination of extracellular ma...

Background: Monolayer electrospun scaffolds have already been used in bone tissue engineering due to their high surface-to-volume ratio, interconnectivity, similarity to natural bone extracellular matrix (ECM), and simple production. Objectives: The aim of this study was to evaluate the dynamic culture effect on osteogenic differentiation and mineralizationi into a compact cellular multilayer ...

objective(s): cao–mgo–sio2 system bioceramics possess good characteristics for hard tissue engineering applications. the aim of the study was to synthesize the nano powder by using a sol-gel method and evaluate of bioactivity in the cells culture. methods: to characterize of powder x-ray diffraction (xrd), transmission electron microscopy (tem) and to evaluate the bioactivity sample cell seedin...

Background: Wharton’s jelly is an unlimited source of stem cells that can be used in cell therapy and tissue engineering without any ethical concern. It has been revealed the cell-free extract could be effective to induce cell differentiation. The objective of this study was to induce Wharton’s jelly-derived mesenchymal stem cells (MSCs) into hepatocyte-like cells by premeabilization of the cel...

Precision Drug Delivery In article number 2206989, Yu Tao, Mingqiang Li, Xuesi Chen, and co-workers report a membrane-fusogenic liposome to precisely convey two glycan-engineering drugs onto the cell membrane into cytoplasm for physical modification of natural-killer-cell-activating glycans biological inhibition immunosuppressing glycans, respectively, thus sufficiently arousing natural killer ...

Abstract Due to their mulitpotency, Mesenchymal stem cells (MSCs), have the ability to proliferate and differentiate into multiple mesodermal tissues. The aim of this study was to isolate MSCs from human Umbilical Cord (hUCMSCs) to determine their osteogenic potential on nanofibrous scaffolds. To this end, Poly (L-lactic acid) (PLLA)/Nano hydroxyapatite (HA) composite nanofibrous scaffolds were...

onsidering the high prevalence of severe organ failures due to the cancer, congenital anomaly, or trauma, and the consequent needs for tissue transplantation, deficiencies in tissues and organs are a huge challenge for regenerative medicine at the moment. More than 40 years have passed since the term ‘tissue engineering’ was created as a new th...